Background: Male infertility is a widespread problem and increased number of mast cells-induced by some drugs like sulpiride atipycal antipsychotic drug, ara described in the testis of males, exhibiting impaired sper-matogenesis and fertility disorders. In this study number of mast cells and sertoli cells, thickness of seminiferous tubule’s lamina propria and sperm concentration and viability i...

In a survey of 36 histologically normal rectal biopsies, plasma cell counts were recorded at different depths of the lamina propria. The necessity of surveying the lamina propria at every level from the muscularis mucosae to the epithelium, in order to obtain an accurate estimate of plasma cell frequency is demonstrated. The relative accuracy of counting smaller areas of lamina propria is teste...

The concentration of IgG and IgA was measured in the supernatants of peripheral blood mononuclear cells and of cells harvested from the intestinal lamina propria, which were cultured in vitro in the presence or absence of mitogens. The lamina propria mononuclear cells were harvested by collagenase digestion of macroscopically normal mucosa from 10 fresh surgical resections for carcinoma. Secret...

BACKGROUND Proteoglycans, consisting of glycosaminoglycan (GAG) side chains covalently linked to a protein core, are a major component of the extracellular matrix of the intestinal lamina propria. AIMS This study investigated the effects of lamina propria T cell activation on the proteoglycan component of the matrix. METHODS The high degree of sulphation of GAGs means that they are polyanio...

CONTEXT Lymphatic vessels are believed to be absent in the colon above the level of the mucularis mucosae. However, in our experience, lymphatic vessels are sometimes identifiable within the lamina propria in the setting of inflammation and neoplasia. OBJECTIVE We sought to assess the presence of lymphatics within the colonic lamina propria in neoplastic and inflammatory conditions using the ...

Using an indirect immunoperoxidase technique we found the numbers of IgG-containing cells in the rectal lamina propria to be increased in patients with ankylosing spondylitis compared with controls, but not in patients with acute anterior uveitis or rheumatoid arthritis, or in the first-degree relatives of patients with ankylosing spondylitis. No differences between diagnostic groups were detec...

objective(s) definite diagnosis of hirschsprung’s disease (hd) is based on histopathological study, but there are limitations associated with standard histology and histochemistry in this regard. the aim of this study was to investigate calretinin immunostaining patterns in both ganglionic and aganglionic hd intestinal specimens and to compare them with control specimens. materials and methods ...

The presence of dendritic cells in human and animal epithelium and subepithelial tissue is demonstrated. The present study used human ileal specimens, resected for carcinoma, and revealed zinc iodide-osmium positive dendritic cells in the crypts of Lieberkühn and throughout the lamina propria. There were more cells in the lamina propria than in the crypts. Dendritic cells were polygonal with mu...

The lamina propria contains a dense network of cells, including interstitial cells (ICs), that may play a role in bladder function by modulating communication between urothelium, nerve fibers and smooth muscle or acting as pacemakers. Transient receptor potential vanilloid 4 (TRPV4) channels allow cation influx and may be involved in sensing stretch or chemical irritation in urinary bladder. Ur...