A study was conducted in albino wistar rats to evaluate the antihypertensive effect of a herbal drug, Lagenaria siceraria in Dexamethasone induced hypertension. Duration of the experiment was 5 days. During the study, aqueous, ethanol, petroleum ether and chloroform extracts of fruits of Lagenaria siceraria were given by orally. The parameter observed was blood pressure. Bloodpressure was measu...

In traditional systems of medicine, different parts (leaves, stem, flower, root, seeds and even whole plant) of Lagenaria siceraria (known as lauki in Hindi), has been used in the ointment for ailment of various diseases throughout India. The fruit of cultivated Lagenaria siceraria is the good source of different nutrients components like protein, fat, fibre, carbohydrates, calcium, magnesium. ...

The leaf of Lagenaria siceraria is considered as a hypolipidemic in folklore medicine. In present investigation, the detailed pharmacognostic study of Lagenaria siceraria leaf is carried out to lay down the standards which could be useful in future experimental studies. The study includes macroscopy, microscopy, preliminary phytochemical screening and physicochemical evaluation.

Article history: Received on: 14/10/2015 Revised on: 04/11/2015 Accepted on: 15/11/2015 Available online: 27/12/2015 The study was undertaken to evaluate milk clotting and proteolytic activity of protein fractions of seeds of Lagenaria siceraria. Protein fractions were isolated by the method of differential solubility, and their protein contents were estimated using Bio-Rad protein assay reagen...

Lagenaria siceraria (Mol.) Standley fruit (bottle gourd), a commonly used vegetable in India is described as cardiotonic and as a general tonic in Ayurveda. Keeping in view the presence of free radical scavenging activity in L. siceraria and involvement of free radicals in the development of various disorders, present studies were designed to evaluate the ethanolic extract of L. siceraria fruit...

The crude ethanolic extract of the root of Lagenaria siceraria (Molina) Standley (Family: Cucurbitaceae), was evaluated for its possible antiinflammatory activity and determination of total flavonoids and tannin contents growing in Bangladesh. The anti-inflammatory activity was studied using carrageenan and histamine-induced rat paw edema test at different doses (200 and 400 mg/kg body weight) ...

The present study was designed to evaluate the cardioprotective effects of Lagenaria siceraria fruit juice in isoproterenol-induced myocardial infarction. Rats injected with isoproterenol (200 mg/kg, s.c.) showed a significant increase in the levels of serum uric acid, tissue Na(++) and Ca(++) ions and membrane-bound Ca(+2)-ATPase activity. A significant decrease in the levels of serum protein,...

OBJECTIVE To elucidate free radical scavenging activity of ethanolic extract Lagenaria siceraria (L. siceraria) (Molina) fruit. METHODS The free radical scavenging activity of the L. siceraria (Molina) fruit extract was assayed by using α,α-diphenyl-β-picrylhydrazyl (DPPH), 2,20-azinobis 3-ethyl benzothiazoline-6-sulfonate (ABTS), FRAP, reducing power, chelating ability and β-carotene bleachi...