AIM To study the dose-response of stage I non-small-cell lung cancer (NSCLC) in terms of long-term local tumor control (LC) after conventional and hypofractionated photon radiotherapy, modeled with the linear-quadratic (LQ) and linear-quadratic-linear (LQ-L) approaches and to estimate the clinical α/β ratio within the LQ frame. MATERIAL AND METHODS We identified studies of curative radiothera...

Liquiritigenin (LQ), an active component of licorice, has an inhibitory effect on LPS-induced inhibitory nitric oxide synthase expression. This study investigated the effects of LQ on choleresis, the expression of hepatic transporters and phase-II enzymes, and fulminant hepatitis. The choleretic effect and the pharmacokinetics of LQ and its glucuronides were monitored in rats. After intravenous...

The Gentzen-Kripke construction of the semantics for intermediate logic LQ, which is obtainable from the intuitionistic propositional logic H by adding the weak law of excluded middle -*A v —• —1>4, is presented. Our construction spans the Gentzen system and the Kripke semantics for LQ by providing the way from the cut-elimination theorem to model-theoretic results. The completeness and decidab...

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Liquiritigenin (LQ), separated from Glycyrrhiza radix, possesses anti-inflammatory, antihyperlipidemic, and antiallergic effects. Our present study aims to investigate the antihepatocellular carcinoma effects of LQ both in cell and animal models. LQ strikingly reduced cell viability, enhanced apoptotic rate, induced lactate dehydrogenase over-release, and increased intracellular reactive oxygen...

In this article, we study the high resolution quantization problem for Rdvalued stochastic processes X that are solutions of stochastic differential equations. We let C([0, 1],Rd) denote the set of continuous functions mapping [0, 1] to Rd and denote by ‖·‖[0,1] the corresponding supremum norm, i.e. ‖f‖[0,1] = supt∈[0,1] |f(t)|. Analogously, Lq([0, 1],Rd) denotes the Lq-space of functions mappi...

A model of irradiated cell survival probability based on cell-cycle regulation of an avascular tumor is developed. It is shown, that for high doses as used in hypofractionated regimens the conventional linear quadratic (LQ) model grossly underestimate cell survival. The surviving fraction of tumor cells in hypoxic and normoxic conditions is calculated as a function of dose for an equivalent tum...

BACKGROUND We evaluated the performance of two different array-based techniques, a bead-based multiplex genotyping method (LQ; digene HPV Genotyping LQ Test, QIAGEN, Germany) and a DNA chip-based method using peptide nucleic acid probes (PANArray; PANArray HPV Genotyping Chip, Panagene, Korea), for detection of human papillomavirus (HPV) and genotyping of high-risk (HR) or probable high-risk (P...

S AbstractWe analyze the robust stability of Inverse LQ regulators for single-input linear systems with uncertain input delay. Unlike the usual LQ regulator, the Inverse LQ regulator has a gain tuning parameter that can be chosen freely to some extent without losing its LQ optimality. Utilizing this freedom we seek the range of tuning parameter that ensures the robust stability against the unce...

Although the cholinesterase inhibitor tacrine has been successfully used for the treatment of Alzheimer's disease, it is known to have hepatotoxic effects. Liquiritigenin (LQ), an active flavonoid in Glycyrrhizae radix, exerts protective effects against liver damage. This study investigated the toxic effect of tacrine on hepatocytes and the beneficial effect of LQ on tacrine intoxication in viv...