The actinomycins produced by Xtreptomyces antibioticus contain 2 moles of n-valine per mole of antibiotic (l-3). However, the biochemical mechanism for the synthesis of n-valine is unknown. Recent radioisotopic experiments have revealed that n-valine, but not the D isomer, is utilized effectively for n-valine synthesis (4). These results provide evidence for the hypothesis that L-valine is an o...

L-valine is a glycogen-type amino acid regarded among the necessary mammalian acids. This an that essential for protein synthesis. N-salicylidene-L-valine gaining lot of attention because its unique structure and increased catalytic cytotoxic activity. We explore chain supramolecular dialkyltin complexes 2, 3, 4 to learn more about this features regarding topological indices. computed first sec...

1. The production of penicillin N, but not that of cephalosporin C, was inhibited by the addition of d-valine to suspensions in water of washed mycelium of Cephalosporium sp. 8650. The production of cephalosporin C was selectively inhibited by gamma-hydroxyvaline. 2. l-[(14)C]Valine was taken up rapidly and virtually completely by suspensions of washed mycelium but d-[(14)C]valine and alpha-oxo...

Clostridium sporogenes has been found to require L-leucine and L-valine for growth in a minimal medium, although valine can be replaced by isobutyrate and leucine by isovalerate. Cells grown in minimal media incorporated significant 14C from [14C]valine into leucine and from [14C]leucine into valine. Growth with [4,5-3H]leucine also resulted in the incorporation of 3H into valine. These results...

It has been reported that conjugating acyclovir, a potent antiviral with low oral bioavailability, to L-valine increases its urinary excretion in rats. However, it was also reported that this increase is not found for the D-valine ester, suggesting that a carrier-mediated mechanism is involved in its intestinal absorption. Therefore, mechanisms involved in the transepithelial transport of L-val...