In recent years our studies of experimental syphilis have centred in the use of the chimpanzee as an animal model for the disease. Chimpanzees have been infected with Treponema pallidum, T. carateum, and T. cuniculi. The characteristics of these infections have been described in part or in whole elsewhere (Brown, Kuhn, Tolliver, and Norins, 1970; Chandler, Kaufmann, and Kuhn, 1972; Kuhn 1970, 1...

We introduce some concepts of generalized invexity for the continuous-time multiobjective programming problems, namely, the concepts of Karush-Kuhn-Tucker invexity and Karush-Kuhn-Tucker pseudoinvexity. Using the concept of Karush-Kuhn-Tucker invexity, we study the relationship of the multiobjective problems with some related scalar problems. Further, we show that Karush-Kuhn-Tucker pseudoinvex...

Sequential optimality conditions provide adequate theoretical tools to justify stopping criteria for nonlinear programming solvers. Here, nonsmooth approximate gradient projection and complementary approximate Karush-Kuhn-Tucker conditions are presented. These sequential optimality conditions are satisfied by local minimizers of optimization problems independently of the fulfillment of constrai...

Joseph Rouse Wesleyan University Thomas Kuhn's philosophical work has helped initiate or reinvigorate many of the central themes in the philosophy of science over the past three decades. His claim that appropriate attention to history could decisively transform familiar philosophical of science views was of course prophetic. Kuhn's discussion of meaning change, incommensurability, and the inter...

Tracheobronchomegaly (Mounier-Kuhn syndrome) is defined as marked cystic tracheobronchial dilatation. Tracheobronchomegaly (TBM) is a rare condition primarily effecting men between the ages of 40 to 50 years. The etiology of TBM is unknown. Pathologically, there is atrophy of the muscular and elastic elements of the trachea and central bronchi. The diagnosis of TBM and the associated pathology ...

Thomas Kuhn [4] has presented a view of the history of science as a succession of “paradigms” which are not completely comparable with each other. Karl Popper [8] has attacked this view as being relativistic and denying that there is objective scientific truth. Popper seems to be saying that in order for science to be objectively true, every two scientific theories must be completely comparable...