vancomycin is a a glycopeptide antibiotic with bacetiocidal effects on gram positive bacteria by interfering with cell wall synthesis. the necessity for monitoring of serum vancomycin concentrations (svcs) has been recently noticed at many institutions because of concerns for its nephrotoxicity. we aimed to describe the svcs monitoring in pediatric patients, in an effort to determine subtherape...

conclusions by controlling the modifiable risk factors and modality of treatment in our study, physicians can reach more effective treatment. results at the end of the study, long-term graft failure was seen in 27 (10.2%) cases. one-year and 2-year graft survival after diagnosis of cancer were 93.6% and 91.7%, respectively. the univariate analysis showed that the incidence of chronic graft loss...

conclusions: using these factors, nephrologists may predict the occurrence of graft loss or death. if the probability of graft loss was higher, physicians can decrease the immunosuppressive medications dosage to decrease the incidence of graft loss. patients and methods: fine-gray model was used for 266 cases with post-transplant malignancy in iran. these patients were followed-up from the diag...

malignant peripheral nerve-sheath tumor (mpnst) is a high-grade malignant tumor of ecto-mesenchymal origin comprising approximately 10% of soft-tissue sarcomas. they tend to occur associated with neurofibromatosis or sporadically. here we report a mpnst at an extremely rare location and behavior causing disappearance of the entire kidney. patient evaluation included clinical, biochemical and ra...

abstract renal medullary carcinoma (rmc) is an uncommon aggressive neoplasm of the kidney. rmc is biologically aggressive with a very poor prognosis, and metastasis is seen in up to 95% of the patients at diagnosis or shortly thereafter. the common sites of metastasis are respectively lymph nodes, lungs, livers, and adrenal glands in order of frequency. the presence of poorly differentiated eos...

BACKGROUND Uro-oncological neoplasms have both a high incidence and mortality rate and are therefore a major public health problem. The aim of this study was to evaluate research activity in uro-oncology over the last decade. METHODS We searched MEDLINE and ClinicalTrials.gov systematically for studies on prostatic, urinary bladder, kidney, and testicular neoplasms. The increase in newly publ...

Kidney neoplasms are common diseases with varying prognoses depending on the subtype of the tumor. The most common solid lesion of the kidney is renal cell carcinoma, and the treatment is typically surgical removal. With increasing use of cross-sectional imaging in the last two decades, the detection of renal lesions has significantly increased, especially in asymptomatic patients who are scann...

Chloroform is carcinogenic in rats, mice, and probably in dogs. Chloroform induced carcinomas of the liver and kidney and malignant tumors in other organs in rats and mice. Liver neoplasms have been described in three strains of mice. Carcinomas of the kidney were found in a first study in mice and in the repeat of that study. Dogs given chloroform developed neoplasms of the liver as well as in...

Renal leiomyomas are not uncommon mesenchymal neoplasms of the kidney, found in 5% of autopsy specimens and comprising 0.3% of all treated tumors. These tumors arise from the smooth muscle cells of the kidney and are mostly located in the renal capsule. Typical imaging features of renal leiomyomas include a peripheral location, well-defined margins, and hyperattenuation on nonenhanced computed ...