Background It has been demonstrated that weight loss improves symptoms in obese subjects with knee osteoarthritis (KOA). A parallel change in cartilage morphology remains to be demonstrated. Purpose To demonstrate a parallel change in cartilage morphology. Material and Methods Obese patients with KOA were examined before and after weight loss over 16 weeks. Target knee joints were radiographica...

Long-term memory (LTM) formation requires de novo gene expression in neurons, and subsequent structural and functional modification of synapses. However, the importance of gene expression in glia during this process has not been well studied. In this report, we characterize a cell adhesion molecule, Klingon (Klg), which is required for LTM formation in Drosophila. We found that Klg localizes to...

A new plate method was developed for rapid screening of Ketogulonicigenium vulgare mutants overproducing 2-keto-l-gulonic acid (2-KLG). The screening methodology took the advantage of the acidity caused by 2-KLG, which changes the color of bromothymol blue (pH indicator) from blue to yellow. Using the proposed method, a mutant, K. vulgare 65, was selected from 20,000 colonies produced by a stra...

BACKGROUND Quantitative measurement of knee joint effusion by ultrasonography has not been well established; however, a categorical measurement (e.g., a ≥4-mm-deep suprapatellar pouch) is recommended. Therefore, the current study aimed to elucidate the association between symptoms of knee osteoarthritis (OA) and the quantitative measurement of suprapatellar effusion by ultrasonography. METHOD...

A new plate method was developed for rapid screening of Ketogulonicigenium vulgare mutants overproducing 2-keto-l-gulonic acid (2-KLG). The screening methodology took the advantage of the acidity caused by 2-KLG, which changes the color of bromothymol blue (pH indicator) from blue to yellow. Using the proposed method, a mutant, K. vulgare 65, was selected from 20,000 colonies produced by a stra...

fuel cells belong to an avant-garde technology family for a wide variety of applications including micro-power, transportation power, stationary power for buildings and other distributed generation applications. the first objective of this contribution is to find a suitable reduced model of a solid oxide fuel cell (sofc). the derived reduced model is then used to design a state estimator. in th...

OBJECTIVES This study looked to analyse the expression levels of microRNA-140-3p and microRNA-140-5p in synovial fluid, and their correlations to the severity of disease regarding knee osteoarthritis (OA). METHODS Knee joint synovial fluid samples were collected from 45 patients with OA of the knee (15 mild, 15 moderate and 15 severe), ten healthy volunteers, ten patients with gouty arthritis...

The typical way for relation extraction is fine-tuning large pre-trained language models on task-specific datasets, then selecting the label with highest probability of output distribution as final prediction. However, usage Top-k prediction set a given sample commonly overlooked. In this paper, we first reveal that contains useful information predicting correct label. To effectively utilizes s...

BACKGROUND Structural pathology may be present in joints without radiographic evidence of osteoarthritis (OA). Ultrasound is a sensitive tool for early detection of osteophytes. Our aim was to explore whether ultrasound-detected osteophytes (in radiographically and clinically normal finger joints) predicted the development of radiographic and clinical hand OA 5 years later. METHODS We include...

1 1 Short title: Update on plant peroxisomes 2 3 Corresponding author: Bonnie Bartel, Rice University, MS-140, 6100 Main Street, 4 Houston, Texas 77005; Phone: 713-348-5602; E-mail: [email protected] 5 6 7 Peroxisome function, biogenesis, and dynamics in plants 8 9 Yun-Ting Kao2, Kim L. Gonzalez2, and Bonnie Bartel* 10 11 Department of Biosciences, Rice University, Houston Texas 77005 12 13 ORCID...