The effects of allopurinol, acyclovir and theophylline on the activity of adenosine deaminase (ADA) were studied in 50 mM sodium phosphate buffer pH 7.5 at 27°C, using a UV– Vis spectrophotometer. Adenosine deaminase is inhibited by these ligands, via different types of inhibition. Allopurinol, as a transition state analog of xanthine oxidase, and acyclovir competitively inhibit the catalytic a...

The effects of allopurinol, acyclovir and theophylline on the activity of adenosine deaminase (ADA) were studied in 50 mM sodium phosphate buffer pH 7.5 at 27°C, using a UV– Vis spectrophotometer. Adenosine deaminase is inhibited by these ligands, via different types of inhibition. Allopurinol, as a transition state analog of xanthine oxidase, and acyclovir competitively inhibit the catalytic a...

Background and Objective: The currentstudy aimed at investigating the histomorphological spectrum of cervical intraepithelial and invasive lesions assessing the diagnostic significance of P16/INK4a and Ki-67 in such lesions, andcorrelatingP16/INK4a and Ki-67 immunoexpression with histologic type and grade.Methods: A total of 60 cases were selectedcomprisi...

electrokinetic remediation is one of the most promising in situ or ex situ processes for decontamination of heavy metals, anions and polar organic compositions from the soil. in this study, we investigated the efficacy of this method in removing mercury from clayey soil (with kaolin to sand weight ratio of 2:1) and from gold mine tailing dam sediment and determined optimum removal conditions. t...

Objective Adenoid cystic carcinoma (ACC) is a rare malignant tumor originating from the salivary glands. It’s rather bland histological appearance that masks its ultimate biological aggressiveness. Evaluation of cell cycle and mitoses have been useful in predicting malignancy in many tumors. Ki-67 antigen is a human nuclear antigen that presents during all active phases of cell cycle. The aim ...

Objectives: Periapical Granulomas (PGs) and Radicular Cysts (RCs), as the most common odontogenic lesions have yet unclear pathogenesis. This study was aimed to compare PCNA and Ki-67 expression in PGs and RCs and evaluate their possible relationship with two lesions. Methods: In this cross-sectional descriptive study, twenty PGs and twenty RCs were evaluated immunohistochemically using an a...

Introdouction: Lichen planus is a chronic, relatively common, dermal mucosa disease. The World Health Organization (WHO) has introduced lichen planus as a premalignant condition. Ki-67 is a protein that can be detected in all active phases of the cell cycle, especially in the G2 and M phases. Considering the major role of Ki-67 in the regulation of the cell cycle and the fact that it is one of ...