introduction: acute renal failure is a common consequence of sepisis due to concurrent renal ischaemia. the role of nitric oxide (no) in endotoxaemia and in ischaemic injury in the kidney is not well defined. material and methods: in this study we have used an animal model of sepsis induced by injection of bacterial lipopolysaccharide (lps) in the rat and measured renal nitric oxide by x-band e...

nitric oxide (no) is implicated as an important mediator of, or intermediary in, inflammation, immunity and neurotransmission. in the kidney, no is involved in haemodynamic regulation, control of vascular tone and tubular function. formation of oxygen-derived free radicals (ofr) have been documented in renal ischaemia- reperfusion before. in this study , we investigated the significance of no f...

myocardial ischemia (mi) resulting in infarction is an important cause of mortality and morbidity worldwide. acute ischaemia rapidly impairs myocardial contractile function. myocardial dysfunction persisting for several hours after transient non-lethal ischaemia, eventually resulting in full functional recovery is termed as myocardial stunning. hibernation is now thought to be the consequence o...

recently a potent anti-inflammatory effect of hydroalcoholic extract of the aerial parts of the sterile stems of stachys inflata has been reported. this study examined whether hydroalcoholic extract isolated from aerial parts of non-flowering stems of stachys inflata (standardized to contain 4.5% caffeic acid derivatives) reduce myocardial infarct size arising from coronary artery occlusion (30...

J Rehabil Med 47 © 2015 The Authors. doi: 10.2340/16501977-1891 Journal Compilation © 2015 Foundation of Rehabilitation Information. ISSN 1650-1977 Objective: To locate and trace endogenous endothelial progenitor cells (EPCs) in rabbits subjected to myocardial ischaemia and/or physiological ischaemia training. Methods: Rabbits were randomly divided into 4 groups: a myocardial ischaemia group (s...

Abstract Background Pre-test probability (PTP) assessment is crucial in the of patients with suspected ischaemia/coronary artery disease. Presently there no established role for artificial intelligence estimating PTP. Purpose Comparison a recently developed memetic pattern based algorithm (MPA) diagnostic power scores predicting ischaemia on positron emission tomography myocardial perfusion ima...

– The high and pointed T wave indicates the first level of ischaemia (level 1 ischaemia). If ischaemia does not progress, it can be suspected that the myocardium is completely protected by coronary and extracoronary collateral circulation9 – ST segment elevation indicates a more advanced stage of ischaemia (level 2 ischaemia), probably due to a conditioning phenomenon10 – The electrocardiograph...

AIMS The study aims (i) to evaluate changes in myocardial ischaemia on single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) after 2 years in a cohort of high-risk patients with diabetes without cardiac symptoms or known coronary artery disease (CAD) and (ii) to assess the value of baseline computed tomography coronary angiography (CTA)-derived coronary atheroscl...

UNLABELLED Mesenteric ischaemia comprises a broad, heterogeneous group of diseases characterised by inadequate blood supply to the small or large bowel. Acute mesenteric ischaemia is a surgical emergency, with significant associated morbidity and mortality. Because the clinical presentation of mesenteric ischaemia is variable and often nonspecific, a high index of clinical and radiologic suspic...