Introduction: Despite the extensive use of ionizing radiation in diagnosis and therapeutic procedures, development of radio-protector agents is important in modulating normal tissue damages. Hesperidin(HES) is a Flavanone glycoside, belonging to the Flavonoid family in human diet abundantly and noted for its many beneficial effects. The aim of present study was investigated to ...

Background: Extensive research has been focused on radiation induced brain injury. Animal and human studies have shown that flavonoids have remarkable toxicological profiles. This study aims to investigate the neuroprotective effects of hesperidin in an experimental radiation induced brain injury. Materials and Methods: 32 adult male Wistar-Albino rats were randomly divided into 4 groups (contr...

Introduction Oxidative stress is a common factor in cataract. Considering the antioxidant properties of hesperidin as a flavanone glycoside from the flavonoid family with radioprotective effect, this study aimed to determine the protective effect of this flavanone glycoside on reducing oxidative stress in the eye lens tissue of mature rats caused by gamma irradiation. Materials and Methods A ...

gamma rays pose enough energy to remove electrons from atoms of absorbing material including human body and adversely affect human health. the external exposure of human beings to natural environmental gamma radiation normally exceeds that from all man-made sources combined. therefore, we monitored gamma dose rate in indoor environments and estimated corresponding annual effective dose in selec...

Human skin cells undergo pathophysiological processes via generation of reactive oxygen species (ROS) upon excessive exposure to ultraviolet B (UVB) radiation. This study investigated the ability of hesperidin (C28H34O15) to prevent apoptosis due to oxidative stress generated through UVB-induced ROS. Hesperidin significantly scavenged ROS generated by UVB radiation, attenuated the oxidation of ...

Background: Hesperidin is a bioflavonoid glycoside mainly found in citrus fruit and has been shown radio-protective potential in various measurement systems. Objective: In this article aims to investigate the radio-protective effect of hesperidin on the liver of Sprague Dawely rats. Material and Methods: In this clinical study, 40 male rats were selected randomly and divided into 8 ...

iran is one of several countries that has regions of high dose natural ionizing radiation. two wellknown villages in the suburb of ramsar town in the caspian sea strip, taleshmahaleh and chaparsar, have background radiation that is 13 times higher than normal. this radiation is the result of radium 226 and radon gas both of which are highly water soluble. while people living in these regions do...

micrornas (mirnas) represent a class of small non-coding rna molecules that regulate gene expression at the post-transcriptional level. they play a crucial role in diverse cellular pathways. ionizing radiation (ir) is one of the most important treatment protocols for patients that suffer from cancer and affects directly or indirectly cellular integration. recently it has been discovered that mi...

background: although ionizing radiation is very important in diagnostic and treatment of many diseases, the hazards of this radiation are considerable and irrefutable. one of the main stages in radiation protection is knowledge about radiation dose in radiological investigation. the aim of this study was to determine the physicians' knowledge in radiological examinations. materials and methods:...