Background: The cornerstone of the treatment of respiratory distress syndrome (RDS) is respiratory support and surfactant replacement therapy. The administration of surfactant through a thin intratracheal catheter is one of the methods used to reduce one of the standard technique complications of a surfactant injection (Intubation-Surfactant-Extubation method [INSURE]). The aim of this study wa...

background:respiratory distress syndrome is the most common respiratory disease in premature neonate and the most important cause of death among them. we aimed to investigate factors to predict successful or failure of insure method as a therapeutic method of rds.methods:in a cohort study,45 neonates with diagnosed rds and birth weight lower than 1500g were included and they underwent insure fo...

BACKGROUND The INtubation-SURfactant-Extubation (INSURE) is a procedure that is increasingly being used to treat the respiratory distress syndrome in preterm infants. The objective of this study was to identify predictors for an unsuccessful INSURE procedure. METHODS The neonates included were less than 32 weeks' gestation, treated with surfactant in the neonatal intensive care unit, and born...

Purpose: To compare respiratory and clinical outcomes between the currently used strategy of Intubation, Surfactant, Extubation (InSurE) and nasal continuous positive airway pressure (NCPAP) and the alternative strategy of InSurE and nasal intermittent positive pressure ventilation (NIPPV) for the initial treatment of respiratory distress syndrome (RDS) in preterm newborns ≤32 weeks. Methods: T...

AIM Preterm infants requiring surfactant replacement have been treated using the INSURE technique, which requires sedation and comprises tracheal intubation, surfactant instillation and extubation. However, minimally invasive surfactant therapy (MIST) does not require sedation, minimises airway injury and avoids placing positive pressure ventilation on an immature lung. This study compared the ...

BACKGROUND Neonatal intubation is a stressful procedure that requires premedication to improve intubation conditions and reduce stress and adverse physiological responses. Premedication used during the INSURE (INtubation, SURfactant therapy, Extubation) procedure should have a very short duration of action with restoration of spontaneous breathing within a few minutes. AIMS To determine the b...

background: various strategies have been suggested for the treatment of respiratory distress syndrome (rds). objectives: the aim of this study was to compare the efficacies of two common methods of rds management among neonates with low birth weight. patients and methods: a cohort study was conducted on 98 neonates with definite diagnosis of rds during 2008-2009. the neonates were divided into ...

administration of endotracheal surfactant is potentially the main treatment for neonates suffering from rds (respiratory distress syndrome), which is followed by mechanical ventilation. late and severe complications may develop as a consequence of using mechanical ventilation. in this study, conventional methods for treatment of rds are compared with surfactant administration, use of mechanical...

The Intubation-Surfactant-Extubation (INSURE) procedure is used worldwide to treat pre-term newborn infants suffering from respiratory distress syndrome, which is caused by an insufficient amount of the chemical surfactant in the lungs. With INSURE, the infant is intubated, surfactant is administered via the tube to the trachea, and at completion the infant is extubated. This improves the infan...

Background: INSURE (Intubation, Surfactant administration, and Extubation) therapy is controversial in managing respiratory distress syndrome (RDS) late preterm newborns. This study aims to determine whether the use of infants with RDS associated improved outcomes compared similar managed CPAP alone. Methods: A retrospective cohort two different neonatal care units treatments Bucaramanga, Colom...