background: recently, different investigators have studied the possibility of radiation therapy in restenosis prevention and have shown promising results. in this study a unique radioactive source for intra vascular brachytherapy (ivbt) was investigated. the two-dimensional dose distribution in water for a 32p ivbt stent has been calculated. the pure beta emitter source 32p has been coated on p...

introduction:  90 sr/ 90 y source  has  been  used  for  the  intravascular  brachytherapy  to  prevent  coronary  restenosis in the patients who have undergone angioplasty. the aim of this research is to determine the  dose distribution of  90 sr/ 90 y source in a water phantom.  materials  and  methods:  in  the  present  work,  mcnp  code  has  been  applied  to  calculate  the  dose  distri...

background and objective: the most common intravascular brachytherapy sources include 32p, 188re, 106rh and 90sr/90y. in this research, skin absorbed dose for different covering materials in dealing with these sources were evaluated and the best covering material for skin protection and reduction of absorbed dose by radiation staff was recognized and recommended. method: four materials includin...

Recent preclinical and clinical studies indicate that irradiation using ionizing radiation in the dose range of 15 to 30 Gy may reduce the occurrence of restenosis in patients who have undergone an angioplasty. Several delivery systems of intravascular brachytherapy have been developed to deliver radiation doses in this range with minimal normal tissue toxicity. In late 1995 the American Associ...

The calibration of a catheter-based system to be used for therapeutic radiation treatment to prevent restenosis following interventional coronary procedures is described. The primary dosimetry was performed ionometrically using an extrapolation chamber equipped with a 1-mm diameter collecting electrode to measure absorbed dose in tissue equivalent plastic at a depth of 2 mm. These results are c...

Since the introduction of percutaneous coronary balloon angioplasty, restenosis has remained the most challenging problem facing interventional cardiologists. Stenting has reduced the need for clinically driven repeat revascularization, but has far from eliminated it. As early as 1989, intravascular brachytherapy was proposed as a means to ameliorate the proliferative component of restenosis af...

Introduction:  90 Sr/ 90 Y source  has  been  used  for  the  intravascular  brachytherapy  to  prevent  coronary  restenosis in the patients who have undergone angioplasty. The aim of this research is to determine the  dose distribution of  90 Sr/ 90 Y source in a water phantom.  Materials  and  Methods:  In  the  present  work,  MCNP  code  has  been  applied  to  calculate  the  dose  distri...

BACKGROUND Re-stenting of in-stent restenosis (ISR) improves acute angiographic results. Methods and Results- Volumetric intravascular ultrasound analysis was performed in 70 ISR lesions that received either placebo (n=36) or (192)Ir radiation (n=34). ISR lesions treated by re-stenting were divided into 3 groups: old stent not re-stented (A), old/new stent overlap (B), and new stent only (C). I...