objective- this study aimed to compare sedation efficacy in intranasal administration of xylazine, diazepam and midazolam with or without ketamine in chough. design- to determine the sedation efficacy, an experimental in vivo study was employed. animals- seven healthy choughs were examined in the current study. procedures- with an interval of one week, seven healthy adult non domesticated choug...

objectives: the aim of the present study was to compare the effects of intranasal ketamine and midazolam on behavior of 3-6 year-old children during dental treatments.   materials and methods: in this randomized cross-over clinical trial, 17 uncooperative children requiring at least two dental treatments were selected and randomly received ketamine (0.5mg/kg) or midazolam (0.2mg/kg) prior to tr...

We addressed the question how long salivary oxytocin levels remain elevated after intranasal administration, and whether it makes a difference when 16 or 24 IU of oxytocin administration is used. Oxytocin levels were measured in saliva samples collected from 46 female participants right before intranasal administration (at 9:30 a.m.) of 16 IU (n = 18) or 24 IU (n = 10) of oxytocin, or a placebo...

Objective- The objective of the present study was to define electrocardiographic data following intranasal administration of diazepam, midazolam and xylazine with or without Ketamine in Chough. Design- To determine the heart effects of anesthetics in intranasal administration, an experimental in vivo study was employed. Animals- Ten healthy Choughs were examined in the current study...

abstract introduction. some children show aggressive uncontrollable behavior during dental procedures, the only way to control this behavior is pharmacological methods such as conscious sedation. recently intranasal administration of midazolam has been considered. the main goal of our study is to determine the effectiveness of intranasal administration of midazolam (in a does of 0.5 mg/kg) in b...

Objective- This study aimed to compare sedation efficacy in intranasal administration of xylazine, diazepam and midazolam with or without ketamine in Chough. Design- To determine the sedation efficacy, an experimental in vivo study was employed. Animals- Seven healthy Choughs were examined in the current study. Procedu...

Exendin, a member of the glucagon-like peptide-1 family, and its antagonist exendin(9-39) affect cognition and neuronal survival after their intranasal delivery. Here, we examined the uptake of radioactively labeled exendin(9-39) (I-Ex) by the olfactory bulbs, brain (minus pineal, pituitary, and olfactory bulb), cerebrospinal fluid, and cervical lymph nodes (C-node) as well as levels in serum a...