The aim of this study was to determine whether adipose derived stem cells (ADSCs) expressing vascular endothelial growth factor (VEGF) gene can improve endothelial function, recover the impaired VEGF signaling pathway and enhance smooth muscle contents in a rat diabetic erectile dysfunction (DED) model. DED rats were induced via intraperitoneal injection of streptozotocin (40 mg/kg), and then s...

The aim of the present study was to examine whether hypoxia preconditioning could improve therapeutic effects of adipose derived mesenchymal stem cells (AMSCs) for diabetes induced erectile dysfunction (DED). AMSCs were pretreated with normoxia (20% O2, N-AMSCs) or sub-lethal hypoxia (1% O2, H-AMSCs). The hypoxia exposure up-regulated the expression of several angiogenesis and neuroprotection r...

Objective(s): The purpose of this study is to determine the efficacy and molecular mechanism of the effect of schisandrin b (SCHB) on treating erectile dysfunction (ED) in a rat model with bilateral cavernous crushing nerve injury. Materials and Methods: The ED rat model was established with bilateral cavernous nerve crushing, and then c...

introduction: world health organization (who) introduced hypertension as an epidemic in developing countries. however, hypertension is adequately controlled in only 12.5% of patients.  the aim of this study was to evaluate the relationship between ramadan fasting and mean arterial pressure (map). methods: this clinical, observational study was carried out at medical o.p.d of jinnah medical coll...

background: hypertension is a risk factor for many diseases. nutritional methods are considered as major tools in lifestyle modification for lowering blood pressure. the present study was conducted to determine the level of dietary adherence in hypertensive patients. methods: this descriptive-analytical study was performed in 2015, on hypertensive patients who were referred to heart clinic of s...

the narrow operating window between pore pressure and fracture pressure makes drilling difficult in some operations. a feasibility study of managed pressure drilling (mpd) is carried out on iran darquain oil field. the previous wells drilled in this field showed that mud returns were lost during drilling gadvan formation. the present work addresses this problem by means of surface back pressure...

introduction pressure ulcers are tissue damages resulting from blood flow restriction, which occurs when the tissue is exposed to high pressure for a long period of time. these painful sores are common in patients and elderly, who spend extended periods of time in bed or wheelchair. in this study, a continuous pressure and temperature monitoring system was developed for pressure ulcer preventio...

objective : this study aims to describe the blood pressure profile of newborns of preeclampsia mothers in vali-e-asr hospital during 2003-2004. materials and methods : in this cross-sectional descriptive analytical study 200 mothers and their newborns were studied. blood pressure of all newborns was checked by oscillometric method on the first day after birth and recorded in a questionnaire alo...

results during the 3 months study, in the placebo group, systolic bp (sbp) increased with 6.3 mmhg and diastolic bp (dbp) increased with 4.6 mmhg, changes which were significant. after the 3 months, the effect of garlic on sbp, after adjusting for baseline value, was significant, and this effect was more significant in hypertensive patients. plasma lipids and lipoproteins did not change signific...