Uveitis is a major cause of vision loss. Methotrexate (MTX) has been widely used in uveitis due to its relatively safe profile. The purpose of this study was to evaluate the effects of two different dosages of MTX via intra-vitreal administration for treatment of endotoxin induced uveitis (EIU) in an experimental model. Thirty-five healthy rabbits were randomly divided into four groups and all ...

Objectives: To see the effects of Intra-Vitreal Diclofenac injection (IVD) in refractory Diabetic Macular Edema (DME).
 Study Design: Quasi-experimental study.
 Place and Duration Study: Retina Clinic, Al-Shifa Trust Eye Hospital, Rawalpindi Pakistan from Sep 2019 to Feb 2020.
 Methodology: Patients included study having Clinically Significant (CSME) with Central Thickness (CMT) ...

BACKROUND Bevacizumab has been in use as a therapeutic agent for macular oedema for several years. While its efficacy has been well documented, its use has been shown to cause a transient rise in the intra-ocular pressure. The aim of this study was to evaluate the long term effect of intravitreal injection of Bevacizumab on Intra-ocular pressure. METHODS One hundred eyes (n=100) of one hundre...

Age-related macular degeneration (ARMD) is the most common cause for visual impairment in the elderly in western countries. Its incidence in India is expected to increase with the increase in the size of geriatric population. Recently several antivascular endothelial growth factor (VEGF) drugs like pegaptanib sodium (Macugen), ranibizumab (Lucentis) and bevacizumab (Avastin) are available for u...

Purtscher and Purtscher-like retinopathies are rare but important to recognize. Its diagnosis is clinical, in which at least 3 of the following diagnostic criteria should be present: 1) Purtscher-flecken (visible in the fundoscopy, they are intra-retinal whitening areas with a clear zone on either side of the vessels), 2) intra-retinal hemorrhages, 3) cotton wool spots (these are located superf...

Objective: To assess the effectiveness and side effects of injecting intra-vitreal moxifloxacin (IV-M) in treatment acute post‑operative (cataract) endophthalmitis having visual acuity ≥ hand movements. Study Design: Prospective, Interventional Case Series study. Setting: Eye Department Qazi Hussain Ahmad Medical Complex, Nowshera. Period: 2018 to Jan. 2021. Material & Methods: Thirty (30) ...