Background and Objective: Morphine can cause harmful effects in the ovaries. The silver nanoparticles (Ag-NPs) used in health care because of antimicrobial properties, can diffuse into the brain blood barrier. This study investigated the protective effect of Ag-NPs on the induction of polycystic ovary (PCO) due to injection of morphine intra-ventromedial hypothalamus (intra-VMH) of rat compared...

the role of the ventromedial nuclei of the hypothalamus (vmn) in food behavior was studied in adult male rats, allocated in 3 groups: control, sham and lesioned. electrolytic lesions were induced stereotaxically (1.2 ma, 15 sec). results revealed a significant decrease (p

Previous studies have reported hyperphagia and obesity in female rats with bilateral lesions of the most posterodorsal part of the amygdala. In rats with unilateral posterodorsal amygdaloid lesions, a dense pattern of anterograde degeneration appears in the ipsilateral ventromedial hypothalamus, but not the contralateral nucleus. In the present study, female rats with unilateral ventromedial hy...

Afferent fibers from the amygdala to subdivisions of lateral, ventromedial and dorsomedial hypothalamic nuclei were investigated in rat by retrograde transport of horseradish peroxidase. Small (intranuclear size) peroxidase deposits were placed in hypothalamic nuclei by iontophoresis of a tracer solution containing poly-L-alpha-ornithine which greatly limited diffusion. The medial, central and ...

MORGANE, P. J. AND A. J. KOSMAN. Relationship of the middle hypothalamus to amygdalar hyperphagia. Am. J. Ph ysiol. I g8(6) : 1315-1318. I g6o.-Stereotaxic lesions in the lateral hypothalamus of the cat at the level of the tuberal region were found not to alter food intake or body weight from preoperative control levels whereas lesions restricted to the ventromedial nuclei produced hyperphagia ...

Hypoglycemia as a limiting factor in the treatment of diabetes mellitus with insulin was apparent even before the hormone was administered to patients. A passage in a biography of Banting notes: ‘The pace picked up as Banting and Best began adjusting extract . . . On December 2, 1921 . . . the injections threw the longevity dog, number 27, into repeated convulsions. . . . It finally died, kille...

Hormonal, Experiential, and Neural Regulation of Ventromedial Hypothalamic Glutamate in the Female Rat Michaela Georgescu, PhD Concordia University, 2010 Previous experiments have shown that enhanced glutamate neurotransmission in the ventromedial hypothalamus by administration of glutamate or its selective receptor agonists kainate, N-methyl-D-aspartic acid or a-amino-3-hydroxyl-5methyl-4-isox...