Laser-enhanced cavitation during high intensity focused ultrasound (HIFU) was studied in vivo using a small animal model. Laser light was employed to illuminate the sample concurrently with HIFU radiation. The resulting cavitation was detected with a passive cavitation detector. The in vivo measurements were made under different combinations of HIFU treatment depths, laser wavelengths, and HIFU...

Introduction Ultrasound is widely applied in the clinical field today, such as ultrasound contrast agent imaging, High Intensity Focused Ultrasound (HIFU), Extracorporeal Lithotripsy, sonodynamic therapy. Some of these have a close relation to the dynamic behavior of micro bubbles and that of a bubble cloud. In an ultrasound imaging, micro bubbles are used as contrast agents. Extracorporeal Foc...

Atomization and fountain formation is a well-known phenomenon that occurs when a focused ultrasound wave in liquid encounters an air interface. High intensity focused ultrasound (HIFU) has been shown to fractionate a tissue into submicron-sized fragments in a process termed boiling histotripsy, wherein the focused ultrasound wave superheats the tissue at the focus, producing a millimetre-sized ...

Attractivity of robotic high intensity focused ultrasound (HIFU) is based largely on the non-invasive, extremely precise nature of this high-tech robotic therapy as well as its clean, radiation free, surgical, but nevertheless, bloodless character. Today, in urological oncology, HIFU is used clinically as a therapeutic tool for the treatment of prostate cancer. Experimentally it is investigated...

Ultrasound (US) thermotherapy is used to treat tumours, located deep in human tissue, by heat. It features by the application of high intensity focused ultrasound (HIFU), high local temperatures of about 90 degrees C and short treating time of a few seconds. Dosage of the therapy remains a problem. To get it under control, one has to know the heat source, i.e. the amount of absorbed US power, w...

Background/introduction Anti-tumor immune response caused by High Intensity Focused Ultrasound (HIFU) therapy has been a subject of controversy. Most agree that the response is more likely to be induced by mechanical, rather than thermal effects of HIFU. The goal of the current work was to study the effect of HIFU-induced liquefaction of a tumor on tumor-specific and non-specific T-cell mediate...

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A new approach for characterizing high intensity focused ultrasound (HIFU) transducers is presented. The technique is based upon the acoustic streaming field generated by absorption of the HIFU beam in a liquid medium. The streaming field is quantified using digital particle image velocimetry, and a numerical algorithm is employed to compute the acoustic intensity field giving rise to the obser...

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