background: influenza a virus is the most virulent human pathogen and causes the most serious problem. having epidemiological knowledge about this disease is important. the aim of this study was to determine the prevalence of influenza a/h3n2 virus infection in northern iran from 2011 to 2013 using the real-time polymerase chain reaction (rt-pcr). methods: in this cross-sectional study 57 sampl...

Background & Aims: Influenza viruses are important causes of mortality and morbidity in children. The aim of this study was to assess the presence of antibodies (IgG) against Influenza A in children in Kerman, Iran. Methods: In a cross-sectional study, 200 children aged 4-14 years referred to Besaat Clinic and Afzalipour hospital for diseases other than influenza were enrolled. Sera were tested...

results: of 655 samples, 69 (10.53%) had positive results for human influenza a virus, and 5 (0.7%) samples had positive results for influenza b. of those 69 samples with positive results for influenza a viruses, 45 (6.8%) were h3n2, and 24 (3.6%) were h1n1 subtypes. in this study most cases with positive results were less than 20 years. the sample positive included 49% males and 51% females. t...

objective this is the first report of cns involvement by the new influenza virus (influenza a [h1n1]) in iran. the patient was a 10-year-old boy with chief complaints of fever, malaise, and cranial nerve involvement, resulting in respiratory muscle paralysis and intubation. this shows that the new influenza virus, as well as the seasonal flu, can cause neurologic complications; however, the sev...

results 111 female and 142 male were available from a total of 253 confirmed h1n1 cases. the minimum and maximum ages were 1.5 and 90 years, respectively. the most common symptoms were fever and cough. 144 cases had record of hospitalization, 100 cases were undergone outpatient treatment and nine cases have not recorded the treatment status. the most frequent underlying manifestation was hypert...

results out of 253 cases confirmed for influenza a (h1n1), 9 women and 11men had died. amongst these cases the minimum and maximum age was3.5 and90 years, respectively. also, from the 20 confirmed cases of influenza a (h1n1) that had died, 16 cases had at least one underlying disease. conclusions there was no significant association between mortality of confirmed cases of influenza a (h1n1) and...

background and aims: influenza a viruses are important pathogens for humans especially in pandemic episodes. two adamantane derivates, amantadine and rimantadine, are used for prophylaxis and treatment of influenza a virus infections. however, single amino acid substitutions in the m2 transmembrane domain which lead to amantadine resistance of these viruses occur at residues 26, 27, 30, 31 or 3...

Abstract : Avian influenza virus (AIV) infection is a major cause of influenza mortality in birds and can cause human mortality and morbidity. Although the risk of infection with avian influenza virus (AIV) is generally low for most people, the pathogenic virus can cross the species barrier and acquires the ability to infect and be transmitted among the human population; therefore the ra...