conclusions results showed that the boiled anethum graveolens seeds was effective on labor induction. results case group had a significantly better bishop score following the intervention compared to the control group. the mean duration of active phase, second and third stages of labor were significantly lower in the case group. the control group had shorter latent phase than the case group. pa...

background: we sought to compare the effectiveness and safety of sublingual versus vaginal misoprostol for the termination of pregnancy with a live full-term fetus. methods: this randomized, triple-blind, placebo-controlled clinical trial was performed on 200 primiparous women with normal, singleton, full-term pregnancies candidated for the induction of labor. sublingual and vaginal tablets con...

OBJECTIVE To compare the normal labor progress of women whose labor was induced with that of women who labored spontaneously. METHODS A retrospective cohort study of all consecutive women admitted for labor at 37 weeks or more of gestation from 2004-2008 who reached the second stage of labor. Women whose labor was induced and women whose labor was augmented were compared with women who labore...

INTRODUCTION Views on the conduct of labor have changed over time, and a significant difference exists in relation to obstetric centers. OBJECTIVE To assess cost, clinical outcomes and cost-effectiveness of different types of labor in singleton pregnancies. METHODS A decision model was used to compare vaginal labor, induced labor and planned cesarean section. All data were taken from the Bo...

Notch signaling pathways exert effects throughout pregnancy and are activated in response to TLR ligands. To investigate the role of Notch signaling in preterm labor, Notch receptors (Notch1-4), its ligand Delta-like protein-1, transcriptional repressor hairy and enhancer of split-1, and Notch deregulator Numb were assessed. Preterm labor was initiated on gestation d 14.5 by 1 of 2 methods: 1) ...

Major basic protein (MBP), the core of the eosinophil granule, is a potent toxin for parasites and mammalian cells; it also causes histamine release from mast cells and basophils. Plasma levels of MBP are increased in all pregnant women, and MBP has been localized by immunofluorescence to placental X cells and placental-site giant cells. Analyses of plasma MBP levels during pregnancy showed a s...

BACKGROUND Preterm birth is now recognized as the primary cause of infant mortality worldwide. Interplay between hormonal and inflammatory signaling in the uterus modulates the onset of contractions; however, the relative contribution of each remains unclear. In this study we aimed to characterize temporal transcriptome changes in the uterus preceding term labor and preterm labor (PTL) induced ...

The present study tested the hypothesis that ERK activation is an essential step in the onset of labor in a rat model of preterm labor. The administration of RU-486, an antiprogesterone agent, to rats induced preterm delivery 22.2 +/- 0.24 h after treatment. Changes in basal signaling events were studied in myometrial tissue from CO(2)-euthanized rats. Rats treated with RU-486 displayed a drama...