objective(s): inflammation is an immune response toward injuries. although inflammation is healing response, but in some condition it will lead to chronic disease such as rheumatoid arthritis, inflammatory bowel disease, atherosclerosis, alzheimer’s and various cancer. indonesian cassia (cinnamomum burmanni c. nees & t. ness) known to contain coumarin, is widely used for alternative medicine es...

Objective(s): Inflammation is an immune response toward injuries. Although inflammation is healing response, but in some condition it will lead to chronic disease such as rheumatoid arthritis, inflammatory bowel disease, atherosclerosis, Alzheimer’s and various cancer. Indonesian cassia (Cinnamomum burmanni C. Nees & T. Ness) known to contain coumarin, is widely used for alternative medicine es...

While being important for its culinary use, cinnamon is also highly valued for providing significant health benefits [1] including lowering blood sugar levels [2-5], reducing heart disease risk factors [5-7], and even addressing neurological disorders [8-10]. High levels of antioxidants are in present in cinnamon and likely contribute to these health benefits. Cinnamon is made from the dried in...

OBJECTIVES Inflammation is an immune response toward injuries. Although inflammation is healing response, but in some condition it will lead to chronic disease such as rheumatoid arthritis, inflammatory bowel disease, atherosclerosis, Alzheimer's and various cancer. Indonesian cassia (Cinnamomum burmannil C. Nees & T. Ness) known to contain coumarin, is widely used for alternative medicine espe...

OBJECTIVE To evaluate the cytotoxic effect of a hexane extract of Cassia alata leaves in A549 lung cancer cells. METHOD Parental A549 lung cancer cells were exposed to various concentrations (100-180 microg/ml) of Cassia alata leaf extract for 24 hours. Following treatment, the cells were evaluated using the 3-(4, 5-Dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) assay to determi...

Kaempferol-3-O-gentiobioside, the major flavonoid glycoside in Indonesian Cassia alata was quantified in various parts of the plant. The mature leaf was found to contain the highest content of this metabolite. A decrease of the flavonoid content in the juvenile leaf during the period of October through December was also observed. The contents ranged from 2.0 to 5.0% and 1.0 to 4.0% in mature an...

AIM OF THE STUDY The main aim was to demonstrate the effects of Cassia auriculata flowers on blood glucose and lipid levels in experimental diabetic rats. METHODOLOGY Aqueous extract of Cassia auriculata flowers was administered orally and different doses of the extract on blood glucose, haemoglobin, glycosylated haemoglobin, serum and tissue lipids, hexokinase and glucose-6-phosphatase in st...

Evaluation of the effect of hydroalcoholic extracts of Cassia occidentalis in mast cell degradation induced by clonidine in Rats. The effect of oral administration of hydroalcoholic extract of Cassia occidentalis leaves on clonidine induced mast cell degradation has been studied and is compared with the effect of oral administration of Sodium cromoglycate as standard on rats. A clonidine result...

Evaluation of the effect of hydroalcoholic extracts of Cassia occidentalis in paw edema induced by Carrageenan in Rats. The effect of oral administration of hydroalcoholic extract of Cassia occidentalis seeds on carrageenan induced inflammation has been studied and is compared with the effect of oral administration of Diclofenac sodium as standard on rats. A carrageenan resulted in paw edema. S...

Medicinal plants are source of important therapeutic aids for alleviating human ailments. The history of drug is intricately interowen with natural products for centuties. In tune with this effort, the objective set for the present investigation is to estimate the phenolic and flavonoid contents in flower extracts of Cassia auriculata and Cassia siamea. The preliminary qualitative screening rev...