Both direct potentiometry and indirect potentiometry are currently used for Na+ testing in blood. These measurement techniques show good agreement as long as protein and lipid concentrations in blood remain normal. In severely ill patients, indirect potentiometry commonly leads to relevant errors in Na+ estimation: 25% of specimens show a disagreement between direct and indirect potentiometry, ...

Platinum(IV) am(m)ine complexes are of interest as potential anticancer pro-drugs, but there are few reports of their acid-base properties. We have studied the acid-base properties of three photoactivatable anticancer platinum(IV)-diazidodiam(m)ine complexes (cis,trans,cis-[Pt(IV)(N(3))(2)(OH)(2)(NH(3))(2)], trans,trans,trans-[Pt(IV)(N(3))(2)(OH)(2)(NH(3))(2)], and cis,trans-[Pt(IV)(N(3))(2)(OH...

Fig. 1. Regression analysis (regression line – continuous – and 95% prediction interval – dashed lines) to evaluate commutability of IRMM BCR-304 (triangle) and NIST SRM 956c (black circles) between direct potentiometry and colorimetry assays for serum lithium. Gray circles identify native serum samples. Commutability of two JCTLM-listed secondary reference materials for two commercial lithium ...

Introduction Careful temperature control is essential for a wide variety of chemical measurements. High-precision potentiometry, for instance, requires thermostatting, since the slope of the straight line E vs log a is highly temperature dependent (E is the measured emf, log a is the logarithm of the activity of species i). The equation describing the relationship between the measured quantity ...

For most chemists, potentiometry with ion-selective electrodes (ISEs) primarily means pH measurements with a glass electrode. Those interested in clinical analysis might know that ISEs, routinely used for the determination of blood electrolytes, have a market size comparable to that of glass electrodes. It is even less well known that potentiometry went through a silent revolution during the pa...