chronic obstructive pulmonary disease (copd) is a condition associated with inflammation in lungs and airways. the impacts of inflammatory process is not limited to respiratory system but extend to extrapulmonary organs with resultant complications involving endocrine, metabolic and cardiovascular systems. the extent and severity of inflammation may be partly estimated by serum measurement of s...

background: diabetes causes the increased concentration of circulatory cytokines as a result of inflammation. considering that pomegranate juice (pj) is known to have antioxidant and anti-inflammatory properties, the purpose of this study was to determine the effects of pj consumption on markers of inflammation in patients with type 2 diabetes (t2d). materials and methods: in a randomized, doub...

introduction: due to side effects of antiinflammatory drugs such as dexamethasone and indomethacin, there is a less tendency to use them. on the other hand, the use of medicinal plants has been common in the treatment of inflammation since ancient times and also, using of the plants is increasing. present research investigated the antiinflammatory effect of the hydroalcoholic extract of capitol...

ocular involvement is seen in approximately 25% of patients with sarcoidosis. uveitis is the most common ocular manifestation, but sarcoidosis may involve any part of the eye. orbital manifestations of sarcoidosis are uncommon with few series in the literature. a 65-year-old woman presented with redness of the right eye and painless, unilateral eyelid swelling. orbital scanning revealed mass in...

traumatic brain injury (tbi) is a significant public health concern in our country, because of placing in top three most common causes of death and substantial direct and indirect costs to society. the incidence of tbi in our country is 1.7 times of international incidence. traumatic brain injury induced by primary and secondary mechanisms that give rise to death and neurologic morbidity in pat...

background: inflammation is involved in development, progression, and complications of atherosclerotic disease. clinical studies have indicated that the level of monocyte chemoattractant protein 1 (mcp-1), il-18, and adhesion molecules correlates with the severity of atherosclerosis and can predict future cardiovascular events. experimental studies have shown pentoxifylline (ptx) reduces these ...

background: galantamine is a drug used for the treatment of alzheimer’s disease and some other cognitive disorders. it is an inhibitor of acetylcholinesterase however, interaction with nicotinic acetylcholine receptors has also been reported. owing to the significant role of cholinergic anti-inflammatory pathways in neuro-immunomodulation, we decided to examine the effect of galantamine on tula...

background medicinal plants are believed to be important sources of new chemical substances with potential therapeutic effects. washingtonia filifera is characterized by its high content of flavonoids. numerous studies suggest that flavonoids have potential for the prevention and treatment of several diseases. objectives this study aimed to investigate the anti-inflammatory activity of the wash...

one of the important reasons for death among the worldwide’s population is trauma which is injury or damage to a biological organism caused by physical harm from an external source. after trauma, the immune system and the early inflammatory immune response activation lead to massive injury. trauma causes activation of nearly all components of the immune system; it also activates the neuroendocr...

objective(s):recently anti-inflammatory effects of antidepressants have been demonstrated. venlafaxine belongs to newer antidepressants with serotonin norepinephrine reuptake inhibition property. the pain alleviating properties of venlafaxine in different pain models such as neurogenic pain, diabetic neuropathy, and fibromyalgia have been demonstrated. anti-inflammatory effects of venlafaxine a...