Implant-related infection is a difficult problem in orthopaedics as it not only leads to failure internal fixation, but also increases the financial burden and perioperative risk on patients. In past, orthopaedic implants were designed mechanical fixation devices simply maintain biological properties, regulate surrounding microenvironment. More recently, antimicrobial biocoatings have been inco...

conventional implant dentistry has been limited to healed edentulous ridges with adequate bone. predictable success rates resulted in using dental implants in compromised situations such as insertion into old infected sites or near to pathological areas. there is significant data about marginal bone loss and lack of osseointegration around the neck of implants. however, the data about peri apic...

AIM Implant-related infections are still a significant problem in spinal surgical procedures. Many drugs and methods have been tried to prevent implant-related infections. Our objective in this study was to evaluate whether royal jelly, which was found to hinder the growth of MRSA, has any preventive role in the prognosis of an infection in rats in an implant-related infection model. MATERIAL...

Infection is a major complication of implantable medical devices, which provide a scaffold for biofilm formation, thereby reducing susceptibility to antibiotics and complicating treatment. Hematogenous implant-related infections following bacteremia are particularly problematic because they can occur at any time in a previously stable implant. Herein, we developed a model of hematogenous infect...

BACKGROUND Periprosthetic bacterial infections represent one of the most challenging orthopaedic complications that often require implant removal and surgical debridement and carry high social and economical costs. Diabetes is one of the most relevant risk factors of implant-related infection and its clinical occurrence is growing worldwide. The aim of the present study was to test a model of i...

peri-implantitis is a site-specifi c infectious disease that causes an infl ammatory process in soft tissues, and bone loss around an osseointegrated implant in function. the etiology of the implant infection is conditioned by the status of the tissue surrounding the implant, implant design, degree of roughness, external morphology, and excessive mechanical load. the microorganisms most commonl...

BACKGROUND AND AIM Sonication is currently considered the best procedure for microbiological diagnosis of implant-related osteoarticular infection, but studies in nail-related infections are lacking. The study aim was to evaluate implant sonication after intramedullary nail explantation, and relate it to microbiological cultures and clinical outcome. PATIENTS AND METHODS A study was performed...

Periprosthetic infection remains a challenging clinical complication. We investigated the antibacterial properties of pure (99.9%) magnesium (Mg) in vitro and in an in vivo rat model of implant-related infection. Mg was highly effective against methicillin-resistant Staphylococcus aureus-induced osteomyelitis and improved new peri-implant bone formation. Bacterial icaA and agr RNAIII transcript...