background : since the introduction of silicone based medical devices in to clinical practice, several reports appeared in the medical literature regarding their adverse effects. however, there are few reports of immunologic reactions to these implants. case presentation : a case of systemic reaction to a breast implant inserted for immediate breast reconstruction in a breast cancer patient is ...

conclusions subcutaneous nodules in the absence of a local reaction at the site of bcg vaccination may be the sole manifestation of disseminated bcg disease. case presentation we report on an 11-months-old boy with prolonged fever and diffuse hyperpigmented subcutaneous nodules. due to lymphopenia, oral thrush and severe adverse reaction to bcg vaccination, the possibility of primary immunodefi...

the primary immunodeficiency (pi) disorders are abnormalities in development and maturation of the immune system. individuals with pi disease may experience frequent infections, which limit their abilities to exhibit physical and psychological well-being secondary to their illness. in this survey we compared health-related quality of life of primary immune deficient patients with healthy childr...

it has been recognized that acute and chronic stress has an impact on the immune system. acute stress may have a stimulating effect on the immune system, while in the case of chronic stress specially depression, the immune system could be down-regulated. however, an association between depression and a higher number of circulating white blood cells with increased activity has been reported. ele...

coincidence of autoimmune diseases such as immune thrombocytopenic purpura (itp) with  immunodeficiencies has  been  reported  previously in  patients  who  suffered  from primary antibody deficiency (pad). but there is no original study on immunological profiles of itp patients to find out their probable immune deficiency. in this case-control study, itp patients’ humoral immunity was investig...

abortion traditionally means miscarriage and is still known as a problem, which societies have been trying to reduce its rate by using legal means. despite the fact that  pregnant women and fetuses have been historically supported;  abortion  was firstly criminalized in 1926 in iran, 20 years after establishment of modern legal system. during next 53 years this situation changed dramatically, t...

primary immunodeficiency diseases (pid) consist of a group of long-term illnesses which had permanent psychiatric effects on the patients and their parents. this study was designed to find out the most important origins and aspects of stressor in parents of pid patients.to assess the  impact of  psychiatric aspects in parents  of pid  patients, a valid and reliable questionnaire was compiled ba...

cow’s milk allergy (cma) is the most frequent food allergy in children and oral immunotherapy (oit) is a promising approach for treatment of patients. the most challenging cases are anaphylactic with coexisting asthma and proposing safe protocols is crucial especially in high risk groups. considering that cma varies among patients, an individualized oit protocol would be beneficial to achieve a...

cytotoxic effects of obturation materials were tested in presence and absence of endotoxin on human monocytes in vitro.human monocytes from thp-1 cell line were cultured. three millimeters from the tip of each resilon and gutta percha points were cut and directly placed at the bottom of the culture wells. cultured cells were exposed to gutta percha (groups g1 and g2) and resilon (r1 and r2). te...