identification of acid-fast bacilli (afb) in sputum or tissue samples is among definite diagnostic methods of tuberculosis. however, this method of diagnosis is restricted by certain limitations.   serologic diagnosis of tuberculosis (tb) has been used for a long time. the aim of this study was to determine the sensitivity and , specificity of antigen 60 (a60) igg, iga, igm test results in tb d...

conclusions based on the findings of the present study, the frequency of toxoplasma infection is high in the studied population, although it is fairly close to the findings of reports from the other areas of iran. results in total, 1910 (29.87%) out of 6393 subjects were found to be infected with toxoplasma gondii. in terms of the seropositivity, 1871 (32.42%) out of 5770 and 128 (2.14%) out of...

since the incidence of symptomatic congenital cytomegalovirus infection is low (~0.05%) and risk factors are not well defined, it is difficult to develop strategies for prevention. the aim of this study was to recognise the utility of specific immunoglobulin g avidity analysis for distinguishing primary infection from past/recurrent infection. sera from 50 women with cytomegalovirus specific im...

The aim of the current research was to investigate the effect of aluminum exposure on humoral immunity (immunoglobulin G and immunoglobulin M serum levels), function enzymes, and histological alterations in the liver of rats. Materials & Methods: Sixteen albino male rats at fifteen weeks were grouped into four groups, and administered with aluminum chloride at 35g/Kg of body weight for 8, 12 ...

As IgM and IgA-enriched preparations are needed to complete the immunotherapeutic spectrum, a simple procedure is described for the preparation of IgM and IgA enriched immunoglobulins. Fraction III which was prepared by cold ethanol fractionation was treated by octanoic acid followed by ethanol precipitation and ion-exchange chromatography using Sephadex DEAE A-50 and 0.1 M tris-D.35M NaCI ...

Background: Waldenstrom macroglobulinemia is a lymphoplasmacytic lymphoma with elevated serum immunoglobulin M and multi-organ involvement. Primary systemic amyloidosis usually develops due to immunoglobulin light chains depositions in different organs due to an underlying gammopathy. Case presentation: Our patient was an 86-year-old man with macroglossia, ecchymotic patches and bullous lesion...

Background: Graves’ disease is an autoimmune disease, characterized by the presence of antibodies directed to TSH receptor or nearby regions as well as antibodies to double strands DNA (dsDNA) anticardiolipin and nuclear antibodies. This study evaluated anticardiolipin and rheumatoid factor, such as IgA and IgM antibodies in patients with Graves’ disease. Patients and methods: Anticardiolipin a...