background and purpose: although molds are regarded as the main fungal allergen sources, evidence indicates that spores of basidiomycota including agaricus bisporus (a. bisporus) can be also found at high concentrations in the environment and may cause as many respiratory allergies as molds. the aim of the present study was to evaluate specific immunoglobulin e (ige) and immunoglobulin g (igg) ...

b ac k gro und : atopic dermatitis (ad) is a prevalent chronic disease in children aging from 6 months to 12 years old. recent studies have shown a positive effect of prebiotics in the prevention and treatment of ad. the mechanism of this effect has not been clearly established. the objective of this study was to investigate the effect of supplementation of prebiotic on serum immunoglobulin e (...

immunoglobulin e is one of the five classes of immonoglobulins that plays an important role in allergic diseases. production of monoclonal antibodies by a single clonotype against different epitopes of immunoglobulin e has high priority in development of diagnostic kits. in this study, an attempt was made to produce monoclonal antibodies against human immunoglobulin e. balb/c mice were immunize...

few biomarkers that can predict the clinical response to allergen immunotherapy (ait) have been identified. the aim of the present study was to investigate parameters that could be used “in predicting the clinical response to ait” in children with asthma caused by house dust mites. we evaluated 107 children with mild persistent asthma who were sensitised only to mite aeroallergens. the study gr...

the clinical behavior of asthma varies with age at onset. this study was undertaken to identify associated markers of adult-onset allergic asthma (age ≥20 years).this cross-sectional study compared two groups: 58 patients with asthma onset at <20 years and 66 with onset at ≥20 years. they were compared depending on results of clinical history, and body mass index (bmi), aeroallergen sensitizati...

hyper - immunoglobulin e syndrome is a rare primary immunodeficiency disease characterized by recurrent abscess formation, respiratory tract infections and very high titers of serum ige associated with peculiar face and skeletal features. we report a seven-year old  girl  presenting with persistent productive cough and  history of chronic eczematoid facial lesions since infancy  and  two episod...

conclusions one in five patients undergoing maintenance dialysis in hamadan is seropositive for hepatitis e immunoglobulin g antibody. future studies are needed to investigate the factors contributing to the observed high prevalence rate and the possibility of parenteral transmission of hepatitis e. results thirty patients (19.2%), were seropositive. seropositive patients were not significantly...

multiple sclerosis (ms) and allergy are believed to up regulate t helper cell type 1 (th1) and t helper cell type 2 (th2) responses, respectively. it has been shown that disequilibrium in the  ratio  of  th1/th2  activities may increase frequency of  one  disease and  decrease the frequency of the other. the aim of this study was to investigate the relation of ms with allergy and atopy in new d...

kimura's disease (kd) is a rare idiopathic condition of unknown etiology. the disease is characterized by swelling and lesions in the head and neck region, with involvement of the subcutaneous soft tissue, major salivary glands and lymph nodes. patients almost always have eosinophilia and elevated serum immunoglobulin e levels. the diagnosis is established by biopsy. kd is usually self limiting...