background: ubiquitin, an 8.5 kda peptide that marks other proteins for proteasomal degradation, tags defective sperm dur­ing epididymal passage. thus, sperm ubiquitination is a universal marker for sperm defects and can be used as a sperm func­tion test. the objective of the present study was to examine the relationships between sperm ubiquiti­nation and clinical se­men parameters, using simpl...

background: immune thrombocytopenia is a hematologic disorder characterized by low platelet count and variable bleeding manifestations due to immune-mediated platelet destruction and/or suppression of platelet production. this study was performed to evaluate characteristics and clinical presentations of adult patients with immune thrombocytopenia and to explore the clinical value of platelet an...

background leptospirosis is a systemic infectious disease caused by pathogenic bacteria belonging to the species of leptospira, it is considered to be the most common zoonosis in the world. this is a serious and sometimes fatal infection which is transmitted from animals to humans by entering the digestive tract or mucosal membrane. within the initial 10-12 day period, the patient may experienc...

background: iga nephropathy, a prevalent disease in asia, is considered the main cause of end stage renal disease among primary glomerular disease. objective: to determine the frequency of different clinical, histopathological and immunofluorescent characteristics of iga nephropathy. methods: renal biopsies of 376 patients were received for immunofluorescent and for histopathological studies. b...

background & objective: autoimmune bullous diseases are associated with autoimmunity against structural components in the skin and mucous membranes. autoantibodies are against the intercellular junctions in pemphigus disease and hemidesmosomal unchoring complex in pemphigiod diseases and epidermolysis bullosa aquisita. the tissue-bound and circulating serum autoantibodies can be detected wi...

background : the aims of this study were to determine the seroprevalence of canine ehrlichiosis and risk factors of this disease in companion dogs’ population of mashhad, north east of iran. canine monocytic ehrlichiosis (cme) is a zoonotic disease transmitted by ticks, rhipicephalus sanguineus, and caused by an obligate intracellular bacterium, ehrlichia canis. methods : during september 2009 ...