background: numerous evidences indicate that in some hiv-1 positive patients, the humoral and cellular immune responses are induced against hiv-1 proteins and this is inversely related to the progress of infection. objective: the aim of this study was the evaluation of the adenovectors containing hiv genes in induction of immune responses in mice. methods: the hiv-1 genes including gag p24, rev...

different medicinal plants have been used in animal and poultry nutrition in last decade. it seems that there are some potential to these medicinal plants to replace with common antibiotics. licorice root (glycyrrhiza glabra) is a medicinal plant that extensively was used in different studies. in the present study, the effect of dietary addition of licorice root on performance and blood energy ...

cortical spreading depression (csd) are associated with dramatic failure of brain ion homeostasis, efflux of excitatory amino acids from nerve cells, increased energy metabolism and changes in cerebral blood flow. there is strong clinical and experimental evidence to suggest that csd is involved in the mechanism of migraine, stroke, subarachnoid hemorrhage and traumatic brain injury. therefore,...

zataria multiflora essential oil possesses immunomodulatory effects and the present study investigatesits effect on immune responses to live newcastle disease (nd) vaccines and faecal shedding period ofvaccine strain virus in chickens. one hundred and eighty chickens from both sexes were divided into 6 equalgroups: group 1: unvaccinated, group 2: vaccinated (b1 vaccine followed by la sota 10 da...

background: rhipicephalus ( boophilus ) annulatus tick is one of the most important ectoparasite of cattle. re­cently, several laboratories in the world have been concentrated on immunizing cattle against tick using various types of tissue extracts of ticks. the aim of this study was to evaluate the effect of immunization of cattle with tick salivary gland extract on biological parameters of ti...

results the results of ifn-γ, il-4 production against antigens, epitopes, and recombinant catalase by t-cells were compared for better understanding of epitope efficiency. conclusions the current research demonstrated that epitope sequence stimulates cellular immune responses effectively. in addition, increased safety and potency as well as a reduction in time and cost were advantages of this m...

background: toxoplasma gondii is an obligate intracellular parasite that infects all mammalian cells. several antigens such as excreted/secreted antigens have been identified as a potential vaccine candidate. objective: to determine how excreted/secreted antigens from peritoneal exudates of infected mice (mesa) stimulate cell-mediated immune responses and induce protective immunity against toxo...

background: cervical cancer is the most prevalent tumor in developing countries and the second most frequent cancer among female population worldwide. specific human papillomaviruses and, most notably, hpv types 16 and 18 are recognized as being caus-ally associated with cervical carcinomas. the early hpv type 16 genes, e6 and e7, di-rectly participate in the in vitro transformation of primary ...

Memory formation is the most important aspect of a vaccine which can guarantee long-lasting immunity and protection. The main aim of the present study was to evaluate the memory immune responses after immunization with a mini vaccine. Mice were immunized with human immunodeficiency virus-1 P24-Nef fusion peptide and then cellular and humoral immune responses were evaluated. In order to determin...

memory formation is the most important aspect of a vaccine which can guarantee long-lasting immunity and protection. the main aim of the present study was to evaluate the memory immune responses after immunization with a mini vaccine. mice were immunized with human immunodeficiency virus-1 p24-nef fusion peptide and then cellular and humoral immune responses were evaluated. in order to determin...