OBJECTIVE There are some controversial studies on effects of anti-epileptic drugs (AEDs) on serum IgG subclasses; however, the role of these medications is still unclear. The aim of this study was evaluation the effects of anti-epileptic drugs on serum concentration of IgG and its subclasses METHODS Serum IgG and IgG subclasses of 61 newly diagnosed epileptic patients were measured at the beg...

Stable aggregated IgG (A-IgG) of various sizes, having high biological activity, were incubated at 4 degree C with adhering peritoneal macrophages from normal rats and the kinetics of A-IgG binding to the cell surface were studied. Equilibrium constants were high (2.8-11.7 X 10(8) M-1) and varied as a function of aggregate size. The maximum number of A-IgG bound per cell varied from 230,000 for...

Influenza A virus causes recurring seasonal epidemics and occasional influenza pandemics. Because of changes in envelope glycoprotein Ags, neutralizing Abs induced by inactivated vaccines provide limited cross-protection against new viral serotypes. However, prior influenza infection induces heterosubtypic immunity that accelerates viral clearance of a second strain, even if the external protei...

saffron (zaaferan), botanical name crocus sativus, is the most expensive spice in the world. it is derived from the dried stigma and pistil of the purple saffron crocus flowers. iran is the largest saffron producer accounting for more than 80% of the world's production. saffron contains an aeroallergen that causes reactive respiratory allergic reactions in atopic subjects. igg antibody to aller...

the objective of this study was to determine the effects of supplemented selenium (se) on plasma cortisol, red blood cell glutathione peroxidase activity (rbc gsh-px-1), concentration of immunoglobulin g (igg) and body weight in pneumonic suckling calves. ten holstein suckling male calves were randomly allocated to two groups and fed either unsupplemented milk (control) or with milk supplemente...

Antibodies to myelin oligodendrocyte glycoprotein (MOG-IgG) or aquaporin 4 (AQP4-IgG) are associated with CNS inflammatory disorders. We directly compared MOG35-55-induced experimental autoimmune encephalomyelitis exacerbated by MOG- and AQP4-IgG (versus isotype IgG, Iso-IgG). Disease severity was highest after MOG-IgG application. administration increased disease incidence Iso-IgG. Inflammator...