background: pentoxifylline (px) is a methyl xanthine derivative that influences the sperm motion characteristics and l-carnitine (l-c) is an amino acid that is naturally produced in the body. in general, separate administration of px and l-c has been reported to be effective on preserving sperm motility in vitro, and also when is consumed orally by the idiopathic oligoasthenoteratozoospermia (i...

conclusions our results show that oxidative stress could play an important role in male infertility as well as in sperm motility and sperm morphology. patients and methods this case control study was conducted using 35 men with idiopathic infertility and 34 men with proven fertility. seminal plasma tac and mda were measured by ferric reducing ability of plasma (frap) and thiobarbituric acid (tb...

INTRODUCTION Infertility affects approximately 15% of all couples, and male factor contribute to up to 50% of cases. Unfortunately, the cause of male infertility is unknown in about 30% of these cases. Infertility of unknown origin is classified as idiopathic male infertility when abnormal semen parameters are present. Despite not having a definable cause, these men may respond to treatment. Th...

In this study, we investigated the association between six genetic polymorphisms (MTHFR C677T and A1298C, NFKB1 -94ins/del ATTG, NFKBIA 3’UTR A>G, DAZL A386G (T54A) and CYP1A1 T3801C) and the risk of idiopathic male infertility in a Chinese population. A case-control study comprising 1,759 idiopathic male infertile patients of Han Chinese ethnicity and 1,826 healthy fertile control individuals ...

Human Andrology 2011, 1:2–16 Objective To highlight the concept of unexplained male infertility and discuss the potential causes and its proper management. Design Review of literature. Results Male infertility of unknown origin is a condition in which fertility impairment occurs spontaneously or due to an obscure or unknown cause. It includes two categories, unexplained male infertility and idi...