نتایج جستجو برای: INA

تعداد نتایج: 1934  

Journal: :Molecular biology and evolution 1994
A R Edwards R A Van den Bussche H A Wichman C S Orser

Bacterial ice nucleation activity (INA+ phenotype) can be traced to the product of a single gene, ina. A remarkably sparse distribution of this phenotype within three bacterial genera indicates that the ina gene may have followed an unusual evolutionary path. Southern blot analyses, coupled with assays for ice-nucleating ability, revealed that within four bacterial species an ina gene is presen...

Journal: :Vaccine 2011
Anuj Sharma Paridhi Gupta Pamela J Glass Michael D Parker Radha K Maheshwari

We have previously shown that a hydrophobic alkylating compound, 1,5-iodonaphthyl-azide (INA) can efficiently inactivate the virulent strain of Venezuelan equine encephalitis virus (VEEV), V3000 in vitro. In this study, we have evaluated the safety of INA-inactivated V3000 and V3526 and the protective efficacy of INA-inactivated V3000. INA-inactivated V3000 and V3526 did not cause disease in su...

Journal: :General physiology and biophysics 1988
E Koppenhöfer R G Sommer

The effect of changes in the holding potential on peak sodium currents in isolated myelinated nerve fibres (peak INa) was investigated with the conventional sodium inactivation being kept at h infinity = 1. In Ringer solution no stationary values of peak INa could be obtained over the potential range tested. Near the normal resting potential, ER, peak INa changed with time clearly even after 10...

Journal: :The Journal of General Physiology 1991
R C Huang R Gillette

cAMP-activated Na+ current (INa,cAMP) was studied in voltage-clamped neurons of the seaslug Pleurobranchaea californica. The current response to injected cAMP varied in both time course and amplitude as the tip of an intracellular injection electrode was moved from the periphery to the center of the neuron soma. The latency from injection to peak response was dependent on the amount of cAMP inj...

Journal: :Al-Mishbah | Jurnal Ilmu Dakwah dan Komunikasi 2017

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 1998
M S Gold J D Levine A M Correa

A tetrodotoxin-resistant voltage-gated Na+ current (TTX-R INa) appears to be the current primarily responsible for action potential generation in the cell body and terminals of nociceptive afferents. Although other voltage-gated Na+ currents are modulated by the activation of protein kinase C (PKC), protein kinase A (PKA), or both, the second messenger pathways involved in the modulation of TTX...

2011
Mitsunori Maruyama Bai-Yan Li Hanying Chen Xuehong Xu Long-Sheng Song Silvia Guatimosim Wuqiang Zhu Weidong Yong Wenjun Zhang Guixue Bu Shien-Fong Lin Michael C. Fishbein W. Jonathan Lederer John H. Schild Loren J. Field Michael Rubart Peng-Sheng Chen Weinian Shou

voltage-gated sodium current INa in MyHC-FKBP12 ventricular cardiomyocytes, a slower recovery of INa from inactivation, shifts of steady-state activation and inactivation curves of INa to more depolarized potentials, and augmentation of late INa, suggesting that the arrhythmogenic phenotype of MyHC-FKBP12 mice is attributable to abnormal INa. Ventricular cardiomyocytes isolated from FKBP12 / My...

2013
Ja Hee Suh Chul-Kee Park Sung-Hye Park

Alpha-internexin (INA) is a proneuronal gene-encoding neurofilament interacting protein. INA is overexpressed mostly in oligodendroglial phenotype gliomas, is related to 1p/19q codeletion, and is a favorable prognostic marker. We studied INA expression in oligodendrogliomas (ODGs) and glioblastomas (GBMs) to verify its association with several molecular phenotypes, 1p/19q codeletion, and epider...

2009
Peter H. Starke

The Petri net tool INA is a well known tool by the Petri net community. However, it lacks a graphical environment to cerate and analyse INA models. Building a modelling tool for the design and analysis from scratch (for INA tool for example) is generally a prohibitive task. Meta-Modelling approach is useful to deal with such problems since it allows the modelling of the formalisms themselves. I...

Journal: :Journal of bacteriology 1983
L M Kozloff M A Schofield M Lute

Chemical and biological properties of the ice nucleating sites of Pseudomonas syringae, strain C-9, and Erwinia herbicola have been characterized. The ice nucleating activity (INA) for both bacteria was unchanged in buffers ranging from pH 5.0 to 9.2, suggesting that there were no essential groups for which a change in charge in this range was critical. The INA of both bacteria was also unaffec...

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