نتایج جستجو برای: IL-21

تعداد نتایج: 382409  

Journal: :Science-Business eXchange 2009

Journal: :Journal of Clinical & Cellular Immunology 2016

2011
Silvano Ferrini Marina Fabbi

The IL21R gene is comprised of 9 exons (+2 alternative first exons), spanning 48.4kb on chromosome 16p11 (Parrish-Novak, 2000). The human IL21R promoter region, contained within nucleotides -789 to +195 (relative to the start of exon 1a) induces the high levels of transcription in reporter assays (Ueda, 2002). A critical SP1 binding site is contained in the region from -80 to -20 and is essenti...

2016
Li-juan Guan Jin-an Zhang

Interleukin-21 (IL-21), the member of the γ-chain-related cytokine family, and its receptor (IL-21R), has been evidenced involving in the immune response, resulting in the development of autoimmune diseases, infectious diseases and tumors. This short communication reviews an overall outline of its genetic variants and expression in autoimmune diseases. It focuses on a series of recent studies t...

Journal: :Journal of Clinical & Cellular Immunology 2011

Journal: :Nature Reviews Immunology 2014

Journal: :Nature Reviews Immunology 2010

Journal: :Nature Reviews Immunology 2011

Journal: :F1000Research 2016

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