background: providing high-quality care in the intensive care units (icus) is a major goal of every medical system. nurses play a crucial role in achieving this goal. one of the most important responsibilities of nurses is sedation and pain control of patients. the present study tried to assess the effect of nurses’ practice of a sedation protocol on sedation and consciousness levels and the do...

clonidine has sedative and analgesic properties. randomized studies examining these properties in mechanically ventilated icu patients are scarce. this study was designed to assess the impact of clonidine on sedative agent use in mechanically ventilated patients.in a prospective, randomized, double blind, placebo-controlled study in a general icu of a university medical center in tehran, iran, ...

BACKGROUND Volatile sedation in the intensive care unit (ICU) may reduce the number of adverse events and improve patient outcomes compared with intravenous (IV) sedation. We performed a systematic review and meta-analysis comparing the effects of volatile and IV sedation in adult ICU patients. METHODS We searched the PubMed, Embase, Cochrane Central Register, and Web of Science databases for...

STUDY OBJECTIVES To determine whether sedation with propofol would lead to shorter times to tracheal extubation and ICU length of stay than sedation with midazolam. DESIGN Multicenter, randomized, open label. SETTING Four academic tertiary-care ICUs in Canada. PATIENTS Critically ill patients requiring continuous sedation while receiving mechanical ventilation. INTERVENTIONS Random allo...

BACKGROUND The majority of critically ill patients experience distress during their stay in the Intensive Care Unit (ICU), resulting from systemic illness, multiple interventions and environmental factors. Providing humane care should address concomitant treatment of pain, agitation and delirium. The use of sedation and approaches to ICU delirium should be monitored according to structured guid...

PURPOSE OF REVIEW There are many new and exciting studies in the sedation literature. Recent studies of new scoring systems to monitor sedation, new medications, and new insights into post-intensive care unit (ICU) sequelae have brought about interesting ideas for achieving an adequate level of sedation of our patients while minimizing complications. RECENT FINDINGS The recent literature focu...

Purpose This evaluation compares propofol and benzodiazepine sedation for mechanically ventilated patients in intensive care units (ICUs) in order to identify the potential economic benefits from different payers' perspectives. Methods The patient-level simulation model incorporated efficacy estimates from a structured meta-analysis and ICU-related costs from Italy, Germany, France, UK, and t...

SUBSTANTIAL efforts have been made over the past decade to focus more attention on sedation and analgesia management in critically ill patients. Although evidence is accumulating of painful and unpleasant experiences suffered during length of stay in the intensive care unit (ICU) that can affect quality of life, even after discharge, more is also known about the impact of excessive use of sedat...

OBJECTIVE The updated clinical practice guidelines for the management of pain, agitation, and delirium recommend either daily sedation interruption or maintaining light levels of sedation as methods to improve outcomes for patients who are sedated in the ICU. We review the evidence supporting both methods and discuss whether one method is preferable or if they should be used concurrently. DAT...

Introduction Sedation is used almost universally in the care of Intensive Care Unit (ICU). The action and side-effects of intravenous drugs in the severely ill patient population of an ICU are difficult to control. The AnestheticConserving Device (AnaConDa) can be used to administer inhaled anesthetics using an ICU ventilator. Inhaled sedation is efficient and easily controllable; in low concen...