OBJECTIVE This study aimed to compare the clinical outcomes between in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) in sibling oocytes. Additionally, we evaluated whether the implementation of split insemination contributed to an increase in the number of ICSI procedures. METHODS A total of 571 cycles in 555 couples undergoing split insemination cycles were included i...

Partial or complete fertilization failure after IVF was reported in 5-10% of cycles. Total fertilization failure in patients with normal sperm parameters is rare but very stressful incident after IVF. To rescue the IVF cycles after total fertilization failure, ICSI of unfertilized oocytes after initial insemination has been reported.We reviewed a 2 years experience of rescue ICSI and analyzed t...

During the last decades, many studies have shown the possible influence of sperm DNA fragmentation on assisted reproductive technique outcomes. However, little is known about the impact of sperm DNA fragmentation on the clinical outcome of frozen-thawed embryo transfer (FET) from cycles of conventional in vitro fertilization (IVF) and intra-cytoplasmic sperm injection (ICSI). In the present stu...

IMPORTANCE Intracytoplasmic sperm injection (ICSI) is increasingly used in patients without severe male factor infertility without clear evidence of a benefit over conventional in vitro fertilization (IVF). OBJECTIVE To assess national trends and reproductive outcomes for fresh IVF cycles (embryos transferred without being frozen) following the use of ICSI compared with conventional IVF with ...

abstract background: fertilization failure is one of the most problems in assisted reproduction technology (art). objective: the aim of this study was the evaluation of oocytes activation by addition of calcium ionophore in unfertilized oocytes in icsi cycles. materials and methods: this study was done on 15 icsi cycles (stimulated with standard long protocol). mature retrieved oocytes with nor...

Intracytoplasmic sperm injection (ICSI) has resulted in pregnancy and birth for many couples, including those with severe male factor infertility. However, even after ICSI, complete failure of fertilization occurs in 1-3% of cycles. Most cases occur due to low number of mature oocytes, failure of oocyte activation or non-availability of appropriate spermatozoa for injection. Given the significa...

OBJECTIVE Laser-assisted intracytoplasmic sperm injection (LA-ICSI), also known as micro-opening or thinning of the zona pellucida (ZP) prior to ICSI, may help to reduce mechanical damage to the oocyte during the procedure. The aim of the present study was to evaluate and analyze the efficacy of our institutional LA-ICSI program, which features laser-assisted ZP thinning prior to ICSI, in compa...

BACKGROUND There is considerable uncertainty as to the significance of a high sperm DNA fragmentation index (DFI) for achieving a successful pregnancy. METHODS The sperm DFI of 124 patients undergoing 192 IVF cycles and of 96 patients undergoing 155 ICSI cycles was determined using the sperm chromatin structure assay on neat sperm. RESULTS The rate of continuing pregnancies in ICSI cycles (...

Objective The present study was designed to evaluate the effect of couple`s obesity simultaneously on in-vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) outcomes. MaterialsAndMethods This cross-sectional study was performed in Royan institute between January 2013 and January 2014. The recorded data of all patients during this time period were evaluated. The study population was ...

OBJECTIVE The aim of this study was to evaluate the efficiency of the intracytoplasmic morphologically selected sperm injection (IMSI) technique compared with conventional ICSI and previous ICSI attempts in oligo-astheno-teratozoospermia (OAT) patients. METHODS The sperms were selected under high magnification (6,600×) and used to induce fertilization in previous ICSI patients by IMSI. These ...