in an effort to evaluate the hypoglycemic activity of t. polium, the crude extract was administered orally to a group of streptozotocin induced diabetic rats for 6 consecutive weeks. significant decrease in blood glucose by 64%, total bilirubin by 35%, glutamate oxaloacetate transferase by 48% and glutamate pyruvate transferase by 30% was observed compared to untreated diabetic rats. however, t...

the rhizome of anemarrhena asphodeloides is used as food and traditional chinese medicine for its hypoglycemic effect. the aim of this study was to investigate the isolation, purification and hypoglycemic activity of anemaran as the active component. the influence factors (isolation duration, ratio of residuals to water and extracting times) during the isolation process were evaluated. the opti...

this study was conducted to evaluate the hypoglycemic, hypocholesterolemic and antioxidant properties of mentha spicata (labiateae) leaves aqueous extract (msla) in alloxan-induced diabetic rats. in this study, hyperglycemia was induced in male rats by intraperitoneal injection of alloxan monohydrate (150 mg/kg). the aqueous extract of m. spicata was orally administered at a dose of 300 mg/kg b...

background and objectives: calamus rotang is used in traditional medicine. regarding the previous phytochemical screening of methanol extract of calamus rotang l. fruits (mcr), this study was performed to find out the antidiarrheal and hypoglycemic effects of the experimented extract in rodents. methods: castor oil induced diarrheal test was followed for screening anti-diarrheal effect of mcr. ...

The chickpea, a food and medicine used by the people of Xinjiang, has a beneficial hypoglycemic effect. To better utilize this national resource and develop hypoglycemic agents from components of the chickpea, a series of new derivatives of isoflavone compounds from the chickpea were synthesized. An insulin-resistant (IR) HepG2 cell model was used to screen the hypoglycemic activities of these ...

PURPOSE Reports of serial magnetic resonance imaging (MRI) in hypoglycemic encephalopathy were limited because MRI is not routinely performed in these patients. Here we present one patient with a history of hypoglycemic encephalopathy and discuss sequential neuroimaging findings. CASE REPORT A 53-year-old male mistakenly took oral hypoglycemic agents developed hypoglycemic encephalopathy. Imm...

Neurotransmitter receptor functional regulation plays an important role in controlling the excitability and responsiveness of hippocampal neurons. Deregulation of its function is associated with seizure generation, motor deficits, and memory impairment. In the present study we investigated the changes in hippocampal cholinergic and GABA receptor binding and gene expression in insulin-induced hy...

objectives insulin resistance has been considered as the most important component of type 2 diabetes mellitus (dm2). plants used in folk medicine to treat diabetes mellitus represent a viable alternative for the control of this disease. this study was aimed to examine the antidiabetic effects of three iranian medicinal plants i.e. urtica dioica, trigonella foenum-graecum and fumaria officinalis...