a three-month-old male native puppy with lameness, metaphyseal swelling, pain, depression,inappetence and variable pyrexia was diagnosed as having hypertrophic osteodystrophy (hod) based onradiologic examination. the hemogram and biochemical profiles were within normal limits. radiologicexamination revealed a radiolucent zone in the metaphyses and a radiopaque band near the physes of theappendi...

A three-month-old male native puppy with lameness, metaphyseal swelling, pain, depression,inappetence and variable pyrexia was diagnosed as having hypertrophic osteodystrophy (HOD) based onradiologic examination. The hemogram and biochemical profiles were within normal limits. Radiologicexamination revealed a radiolucent zone in the metaphyses and a radiopaque band near the physes of theappendi...

Hypertrophic osteodystrophy (HOD) is a major manifestation of the hyper-inflammatory syndrome, and causes high fever, pain and lameness associated with swelling of the growth plates in the femur and humerus. This is typically seen in one or two puppies in a genetically susceptible litter, soon after they receive multivalent vaccination, although it also can occur after monovalent vaccination. O...

ABST RACT The case report describes a Border collie puppy diagnosed with trapped neutrophil syndrome (TNS), an autosomal recessive inherited neutropenia. The report describes the clinical presentation, the course of the disease and diagnosis. Chronologically it appeared that that vaccination may have been a potential initiating factor in instigating the TNS in the puppy. The puppy also develope...

A 6-year survey (1 October 2006 – 1 October 2012) on the prevalence of developmental skeletal abnormalities in dogs was performed based on patients’ records of the Small Animal Clinic to the Faculty of Veterinary Medicine – Stara Zagora, Bulgaria. From the total number of 6,097 dogs with surgical disorders, developmental skeletal disorders were diagnosed in 230 dogs (3.78%). The incidence of di...

Pathologic femoral neck fracture due to renal osteodystrophy is rare. We report the case of a young adult patient with chronic renal failure who presented with bilateral spontaneous femoral neck fractures due to renal osteodystrophy. The pathophysiology of renal osteodystrophy and the treatment of hip fractures in patients with renal failure is discussed.

ABST RACT The case report describes a Border collie puppy diagnosed with trapped neutrophil syndrome (TNS), an autosomal recessive inherited neutropenia. The report describes the clinical presentation, the course of the disease and diagnosis. Chronologically it appeared that that vaccination may have been a potential initiating factor in instigating the TNS in the puppy. The puppy also develope...

BACKGROUND/AIMS Renal osteodystrophy and eventually osteoporosis are serious long-term complications in children with end-stage renal disease before and after renal transplantation. Strontium (Sr) salts are used for treatment of osteoporosis in adults. METHODS To evaluate the time-dependent effects of Sr on growth plate morphology and their reversibility, chronic renal failure (CRF) rats rece...