conclusions our study showed severe neonate indirect hyperbilirubinemia is still prevalence in fars province and ethnic and cultural background of the mothers was more effective than school education in preventing hyperbilirubinemia complication. patients and methods all infants less than 28 days referred due to severe indirect hyperbilirubinemia were included. complete history, physical examin...

The serum bilirubin level of Japanese newborn infants in their first few days is significantly higher than that in Caucasian newborn infants, suggesting that there might be genetic risk factors for the development of neonatal hyperbilirubinemia in the Japanese population. Recently, it has been reported that a variant TATA box in the promoter region of the bilirubin UDP-glucuronosyltransferase 1...

BACKGROUND Today, Severe hyperbilirubinemia is the most common cause of neonatal readmissions. Identification of the cause of neonatal hyperbilirubinemia is useful in determining whether therapeutic interventions can prevent severe hyperbilirubinemia. OBJECTIVES We conducted this study to estimate the incidence of severe hyperbilirubinemia in Fars province and to determine the underlying caus...

OBJECTIVE The clinical significance of postoperative hyperbilirubinemia after heart transplantation has not been reported. Here, we sought to evaluate the incidence, risk factors, and prognosis of postoperative hyperbilirubinemia after heart transplantation. METHODS Between 1987 and 2005, 256 consecutive patients undergoing heart transplantation were studied prospectively. Postoperative hyper...

OBJECTIVES Extreme hyperbilirubinemia (plasma bilirubin ≥ 24.5 mg/dL) is an important risk factor for severe bilirubin encephalopathy. Several risk factors for hyperbilirubinemia are known, but in a large number of patients, a causal factor is never established. UGT1A1 is the rate-limiting enzyme in bilirubin's metabolism. The genotype of Gilbert syndrome, the UGT1A1*28 allele, causes markedly ...

Background: Neonatal Hyperbilirubinemia is a common problem encountered in neonates and often requires admission and treatment. Aims & Objectives: To determine the incidence, etiology and risk factors associated with neonatal hyperbilirubinemia in a tertiary care hospital. Materials and Methods: A retrospective study was conducted on data obtained on live births for 2012 and 2013.All treated ca...

Hyperbilirubinemia is frequently observed in Caucasian HIV patients treated with atazanavir. UDP-glucuronosyltransferase 1A1 polymorphism, UGT1A1*28, which is associated with atazanavir-induced hyperbilirubinemia, is less common in Asians than in Caucasians. However, little is known about the incidence of atazanavir-associated hyperbilirubinemia in Asian populations. Our objective was to invest...

introduction:  inadequate intake of breast milk in the first days of life leads to weight loss in neonates. jaundice is also more prominent in these infants. in this cross-sectional study, we tried to evaluate the extent of weight loss in term breastfed infants who were hospitalized for idiopathic hyperbilirubinemia. methods: this prospective study involved 1072 infants >48 hours old, who were ...

Hyperbilirubinemia is very common and usually benign in the term newborn infant and the late preterm infant at 35 to 36 completed weeks’ gestation. Critical hyperbilirubinemia is uncommon but has the potential for causing long-term neurological impairment. Early discharge of the healthy newborn infant, particularly those in whom breastfeeding may not be fully established, may be associated with...

Hyperbilirubinemia is an important health problem in newborns. The most common causes are Rh and ABO incompatibility, hemolytic anemias, enzyme deficiencies, sepsis, hypothyroidism, pyloric stenosis and breast-milk jaundice. Adrenal hemorrhage is a rare cause of hyperbilirubinemia in the neonate. We present a six-day-old newborn with hyperbilirubinemia and suprarenal hematoma who was born at ho...