metalloporphirins; cu(tpp), mn(tpp)cl, co(tpp), fe(tpp)cl, zn(tpp) and mn(obp)cl catalyze region and chemoselective silylation of hydroxyl groups with hmds. fe(tpp)cl is the most effective catalyst and silylation occurs immediately in its presence at room temperature.

objective(s):non-alcoholic steatohepatitis (nash), is an important component of non-alcoholic fatty liver disease (nafld) spectrum, which progresses to the end stage liver disease, if not diagnosed and treated properly. the disproportionate production of pro- and anti-inflammatory adipokines secreted from fat contributes to the pathogenesis of nash. in this study, the comparative effect of piog...

Objective(s):Non-alcoholic steatohepatitis (NASH), is an important component of Non-alcoholic fatty liver disease (NAFLD) spectrum, which progresses to the end stage liver disease, if not diagnosed and treated properly. The disproportionate production of pro- and anti-inflammatory adipokines secreted from fat contributes to the pathogenesis of NASH. In this study, the comparative effect of piog...

Metalloporphirins; Cu(TPP), Mn(TPP)Cl, CO(TPP), Fe(TPP)Cl, zn(TPP) and Mn(OBP)Cl catalyze region and chemoselective silylation of hydroxyl groups with HMDS. Fe(TPP)Cl is the most effective catalyst and silylation occurs immediately in its presence at room temperature.

The last few years have seen a tremendous improvement in the methods used to protect hydroxy groups with trityls. However, there is limited work on the selective protection and deprotection of ambident nucleophiles (e.g. amines, alcohols and sulfurs) with trityls and p-methoxy substituted trityls. Methoxysubstituted trityl functions have been used as N-protecting groups in pro-drugs, designed t...

A new phenylethyl alkyl amide, (10R)-10-hydroxy-N-phenethyloctadecanamide (1), was isolated from the beetle Ambrostoma quadriimpressum Motschulsky. The structure of the amide was determined by NMR and MS. The absolute configuration of compound 1 was confirmed by an asymmetric total synthesis, which was started from L-glutamic acid. The construction of the aliphatic chain was accomplished by the...

The 9-phenyland the 9-(p-tolyl)-xanthen-9-yl groups 2a and 2b are recommended as alternatives to the 4,40-dimethoxytrityl group 1 for the protection of the 50-hydroxy functions in oligonucleotide synthesis. 2004 Elsevier Ltd. All rights reserved.