in this research, the magnetite nanoparticles (fe304) were prepared by coprecipitation of fe3+ andfe solution in alkaline medium. two kinds of surfactants, cetyl tri methyl ammonium bromide(ctab) and cetyl pyridinum chloride (cpc) were used in the synthesis. fe304 nanoparticles werecoated with human serum albumin (hsa) and bovine serum albumin (bsa). characteristics ofcoated magnetic nanopartic...

background and aims: some nanoparticles can be used in immunoassays to increase sensitivity. this study aimed to evaluate a novel nano-immunoassay based on bovine serum albumin nanoparticles (bsa nps). materials and methods: at first, the nanostructure was synthesized, and then applied as a tag in the nano-immunoassay. then the concentration of β-subunit of human chorionic gonadotropin (βhcg) i...

background: progress in the field of biology and biochemistry has led to the discovery of numerous bioactive peptides and proteins in the last few decades. delivery of therapeutic proteins/peptides has received a considerable amount of attention in recent years. methods: in this study, a two-step desolvation method was used to produce biodegradable hydrophilic gelatin nanoparticles (gnp) as a d...

background: in spermatogenesis, spermatogonial cells differentiate to the haploid gametes. it has been shown that spermatogenesis can be done at in vitro condition. in vitro spermatogenesis may provide an open window to treat male infertility. objective: the aim of this study was to evaluate the effects of a novel scaffold containing human serum albumin (hsa)/tri calcium phosphate nanoparticles...

background and aims: in this lab trial, the effect of scaffold based on human serum albumin (hsa) and hydroxyapatite nanoparticles (ha nps) on mouse spermatogonial cell line (scl) was investigated. materials and methods: to synthesize ha nps, calcium nitrate and diammonium phosphate at ph 13 were gently added and heated at 100 ºc for 24 hours. then serial concentrations of ha nps was separately...

advanced glycation end-products (ages) are formed by non-enzymatic reaction between reducing sugar and protein. ages play important roles in pathogenesis of diabetic, aging complications, endothelial dysfunction and neurological diseases such as the alzheimer’s disease. therefore compounds that prevent the glycation reaction are purported to have therapeutic effect on patients with diabetes and...

Background and Aims: Some nanoparticles can be used in immunoassays to increase sensitivity. This study aimed to evaluate a novel nano-immunoassay based on bovine serum albumin nanoparticles (BSA NPs). Materials and methods: At first, the nanostructure was synthesized, and then applied as a tag in the nano-immunoassay. Then the concentration of β-subunit of human chorionic gonadotropin ...

BACKGROUND Colon cancer is one of the major causes of death in the Western world. Early detection significantly improves long-term survival for patients with the disease. Near- infrared (NIR) fluorescent nanoparticles hold great promise as contrast agents for tumor detection. NIR offers several advantages for bioimaging compared with fluorescence in the visible spectrum, ie, lower autofluoresce...

In this research, the Magnetite nanoparticles (Fe304) were prepared by coprecipitation of Fe3+ andFE solution in alkaline medium. Two kinds of surfactants, cetyl tri methyl ammonium bromide(CTAB) and cetyl pyridinum chloride (CPC) were used in the synthesis. Fe304 Nanoparticles werecoated with human serum albumin (HSA) and bovine serum albumin (BSA). Characteristics ofcoated magnetic nanopartic...