background: a radioprotective effect of amifostine as well as its ability to modulate the level of spontaneous and gamma-irradiation-induced genetic changes on human peripheral blood lymphocytes has been investigated . amifostine, known as a potent radical scavenger, has been introduced as the most effective radioprotector, yet it is not completely approved for the clinical use. however, furthe...

few studies have been conducted on the causative factors associated with the development of cancer. infection by high risk human papillomaviruses (hpvs) have been implicated as causative agents in a variety of cancers. hpv is capable of evading immune system and establishing persistent infections. prolonged infection and lesion maintenance are associated with higher risk of neoplastic progressi...

background: the purpose of this paper is to establish an easy and reliable biodosimeter protocol to evaluate the biological effects of proton beams. materials and methods: human peripheral blood lymphocytes were irradiated using proton beams (let: 34.6 kev μm−1), and the chromosome aberrations induced were analyzed using cytokinesis-blocked (cb) micronucleus (mn) assay. to determine the efficie...

The adaptive response (AR) is a phenomenon by which cells exposure to sublethal doses of DNA-damaging agents (non-mutagenic dose of chemical or radiation), known as conditioning treatment (CT), leads to increased resistance to a subsequent exposure to a higher dose of the same or other agents, known as challenge treatment (CR). The adaptive response (AR) induced by radiation in human lymphocyte...

erythropoietin (epo) was first known as a factor for red blood cell proliferation and differentiation. recent studies show the effects of epo on immune system. in this study the antihuman leukocyte antibody (anti-hla) titer were determined in five groups of rats, which had been sensitized with human lymphocyte. also, the effects of stimulation's frequency and dose of recombinant human eryt...

the adaptive response (ar) is a phenomenon by which cells exposure to sublethal doses of dna-damaging agents (non-mutagenic dose of chemical or radiation), known as conditioning treatment (ct), leads to increased resistance to a subsequent exposure to a higher dose of the same or other agents, known as challenge treatment (cr). the adaptive response (ar) induced by radiation in human lymphocyte...

Erythropoietin (EPO) was first known as a factor for red blood cell proliferation and differentiation. Recent studies show the effects of EPO on immune system. In this study the antihuman leukocyte antibody (anti-HLA) titer were determined in five groups of rats, which had been sensitized with human lymphocyte. Also, the effects of stimulation's frequency and dose of recombinant human erythropo...

stem cells from human exfoliated deciduous teeth (shed) have been introduced recently and  possess characteristics similar to  mesenchymal stem  cells (mscs). because of  their convenient accessibility and safety of harvest, shed can be a preferable source for the ever- increasing mscs’ applications. while they are new, their immunoproperties have not been adequately studied. in this study, we ...

The aim of the paper is to investigate effects of long term x-ray exposure on the human lymphocyte, reactive lymphocyte parameters and morphology of lymphocytes in x-ray technicians at Kirkuk hospitals. The study included 54 apparently healthy male x-ray technicians were matched with another 54 apparently healthy control to show any alteration in the lymphocytes, reactive lymphocytes and morpho...