important aspect of sperm function such as motility and capacitation appear to be mediated at least partially though hyaloronic acid (ha). present study investigated effects of different doses of ha on sperm motility and vitality in human. sperm was obtained from 20 male from ivf clinic in imam khomeini hospital. sperm motility and vitality in human semen was analyzed according to who criteria ...

in human fertilization, the sperm centrosome nucleates a radial array of microtubules called the sperm aster. the sperm aster is responsible for apposition of male and female pronuclei, and later gives rise to the first meiotic spindle. the objective of this study was to determine microtubule assembly and chromatin configuration in rabbit oocytes following intracytoplasmic injection with human ...

In human fertilization, the sperm centrosome nucleates a radial array of microtubules called the sperm aster. The sperm aster is responsible for apposition of male and female pronuclei, and later gives rise to the first meiotic spindle. The objective of this study was to determine microtubule assembly and chromatin configuration in rabbit oocytes following intracytoplasmic injection with human ...

background: an effect of cryopreservation on human sperm is sublethal cryodamage, in which cell viability post-thaw is lost more rapidly at later times than in fresh cells. objective:  this study examined whether the addition of an antioxidant to cryopreservation medium could improve the post-thaw parameters and evaluation of sperm chromatin quality of cryopreserved human spermatozoa from men w...

background: curcumin has shown to affect sperm motility and function in vitro and fertility in vivo. the molecular mechanism(s) by which curcumin affects sperm motility has not been delineated. since modulation of intracellular ph (phi) and plasma membrane polarization is involved in sperm motility, the present study was conducted to investigate the effect of curcumin on these sperm (human and ...

background: nitric oxide (no) is synthesized from l-arginine by a family of enzymes known as nitric oxide synthases. low concentrations of no is essential in biology and physiology of spermatozoa, but high amounts of no is toxic and has negative effects on sperm functions. moreover, sperm membrane contains high concentrations of polyunsaturated fatty acids that are highly susceptible to oxidati...

Background: Mammalian spermatozoa are characterized by a high proportion of polyunsaturated fatty acids (PUFA) and the membrane structure of spermatozoa plays a crucial role in fertilization. Moreover, dietary fatty acid (FA) influence sperm FA profiles in several species. This study focused on responses to dietary omega-3 fatty acids and comprehensive fatty acid profiles analysis in men as wel...

background: gonadotropin-releasing hormone agonists or antagonists are used in assisted reproductive technique cycles as premature luteinizing hormone secretion inhibition. studies have been reported different and contradictory results on the serum progesterone effect on intra-cytoplasmic sperm injection. objective: the purpose of this study was to evaluate the effect of serum progesterone leve...

Background: The purpose of this study was to examine the impact of Insulin (INS) on human sperm function, in light of a recent proteomic analysis indicating that these cells express the INS receptor (INSR). Materials and Methods: We used Western blot and Immunocytochemical analyses. Results: Immunocytochemical analyses confirmed the presence of INSR in human spermatozoa and localized this recep...

evidence suggests that human sperm chromatin anomalies adversely affect reproductive outcomes and infertile men possess substantially amount of sperm with chromatin anomalies than fertile men. routine semen analysis evaluates parameters such as sperm motility and morphology, but does not examine the nuclear dna integrity of spermatozoa. it has been suggested that altered nuclear chromatin struc...