human cytomegalovirus (hcmv, cmv) is a major infectious complication of renal transplantation. the objective of this survey was to optimize and establish a polymerase chain reaction (pcr) technique for rapid and early detection of cmv disease in renal transplant recipients. in a cross sectional study, a total of eighty-one edta-blood samples were collected as simple nonrandomized (sequential) w...

Viruses, including human cytomegalovirus (HCMV), reprogram cellular metabolism using host metabolic regulators to support virus replication. Alternatively, in response infection, the can use limit

accurate and rapid diagnosis of human cytomegalovirus (hcmv) disease in immunocompromised patients has remained as a challenge. quantitative competitive pcr (qc-pcr) methods for detection of hcmv in these individuals have improved the positive and negative predictive values of pcr for diagnosis of hcmv disease. in this study we used qc-pcr assay, using a co-amplified dna standard, to quantitate...

Human cytomegalovirus (HCMV) is a ubiquitous virus whose sole host is humans. Since HCMV can contagion from person to person through numerous ways, vast populations of humans are infected. HCMV infections can potentially have a range from asymptomatic infection in immuno-competent hosts to life-threatening diseases in organ recipients and patients with AIDS. The present article reviews the occu...

Background: Strain-specific antibodies to human cytomegalovirus (HCMV) glycoproteins B and H (gB gH) have been proposed as a potential diagnostic tool for identifying reinfection. We investigated genotype-specific IgG antibody responses in parallel with defining the gB gH genotypes of infecting viral strains. Methods: Subjects primary (n = 20) or non-primary 25) HCMV infection were studied. The...

human cytomegalovirus (hcmv) is a ubiquitous virus whose sole host is humans. since hcmv can contagion from person to person through numerous ways, vast populations of humans are infected. hcmv infections can potentially have a range from asymptomatic infection in immuno-competent hosts to life-threatening diseases in organ recipients and patients with aids. the present article reviews the occu...

Background: Human cytomegalovirus (HCMV) has been detected in tissue samples from patients with glioblastoma but little is known about the systemic immunological response to HCMV these patients. Objectives: To investigate presence and clinical significance of antibodies levels plasma obtained brain tumors. Materials Methods: HCMV-specific IgG IgM antibody were determined 59 collected tumor incl...

Human cytomegalovirus (HCMV) causes persistent infection in humans and severe diseases in fetus andimmunocompromised individuals. Although HCMV is not currently implicated in human cancer, emerging evidence suggests that HCMV infection might be specifically associated with some human malignancies including glioma. Glioma is one of the most common brain tumors affecting children and adults. In t...