نتایج جستجو برای: Huisgen 1,3-dipolar cycloaddition
تعداد نتایج: 343729 فیلتر نتایج به سال:
The 1,3-Dipolar cycloaddition reactions are the classic reaction in modern synthetic organic chemistry. The concept of these reactions was introduced by Huisgen and his co-workers in the early 1960’s. 1,3-Dipolar cycloaddition reactions are simple but powerful tool for the construction of five membered heterocycles such as isoxazoles, isoxazolines, pyrazoles, pyrazolones, 1,2,4-oxadiazolines et...
In this protocol, we report a novel approach for the synthesis of a new class of heterocyclic 1H-1,2,3-triazole-modified peptidomimetic compounds. The process consists of an Ugi four-component condensation reaction of amines, an isocyanide, an aldehyde and acids followed by a Huisgen 1,3-dipolar cycloaddition reaction with an azide group in the presence of a catalytic amount of CuSO4</...
An α-[Cu(II)-porphyrin]-polyethylene was synthesized for the first time using copper catalyzed 1,3-dipolar azide-alkyne Huisgen cycloaddition yielding highly colored moiety-substituted polyethylene.
Multivalent dendrimeric peptides were synthesized via a microwave-assisted Huisgen 1,3-dipolar cycloaddition between azido peptides and dendrimeric alkynes in yields ranging from 46 to 96%.
Biohybrid amphiphiles have been prepared from terminal azide functionalised polystyrene and an alkyne functionalised peptide or protein via a Cu(I) catalysed Huisgen [3 + 2] dipolar cycloaddition reaction.
The synthesis of three acetylene functionalized BODIPY dyes is described. These dyes are used to fluorescently modify an azido functionalized epoxomicin analogue employing the Huisgen 1,3-dipolar cycloaddition, resulting in a panel of fluorescent epoxomicin derived proteasome probes.
A Th-symmetrical C60 hexakis-adduct bearing 12 peripheral azide groups has been prepared and used to produce functionalized derivatives by the copper mediated Huisgen 1,3-dipolar cycloaddition of azides and alkynes.
A novel bifunctionalized [3]rotaxane based on a triptycene-derived macrotricyclic host was conveniently synthesized. On the basis of the [3]rotaxane, a linear main-chain poly[3]rotaxane was further obtained by the highly efficient Huisgen 1,3-dipolar cycloaddition.
Fullerene hexakis-adducts bearing 12 peripheral carbohydrate moieties have been prepared by grafting sugar derivatives onto the fullerene core through the copper mediated Huisgen 1,3-dipolar cycloaddition of azides and alkynes.
The 1,2,3-triazole is a well-known biologically active pharmacophore constructed by the copper-catalyzed azide–alkyne cycloaddition. We herein reported synthesis of 4-amino-7-chloro-based [1,2,3]-triazole hybrids via Cu(I)-catalyzed Huisgen 1,3-dipolar cycloaddition 4-azido-7-chloroquinoline with an alkyne derivative acetaminophen. compound was fully characterized Fourier-transform infrared (FT...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید