The effects of acute (LD50) and sub-chronic dos Senna podocarpa (Guill. et Perr.) Lock pod on the live mice and rats were studied, respectively. The acute tox any observable lethal effects and the calculated histopathological analysis of the liver, kidney, brain a effect. Behavioral observations and the histopatholog significant differences between the control and the tre marked adverse alterat...

BACKGROUNDS: Diseases affecting the respiratory tract of sheep and goats are one of the most important factors which limit production of these species on a world-wide basis. OBJECTIVES: The main goal of this study was to determine Adenovirus (AdV) antigen in formalin-fixed paraffin-embedded lung tissue of pneumonic goats, using immunohistochemistry (IHC) staining method. METHODS: For this purpo...

Malignant transformation in a mature cystic teratoma of the ovary is rare. The most common malignancy is squamous cell carcinoma, which consists of about 75% of malignant transformations. In the present report, we describe a case of advanced-stage squamous cell carcinoma arising in a mature cystic teratoma. A postmenopausal 63-year-old woman with squamous cell carcinoma arising in a mature cyst...

The current survival of patients with breast cancer liver metasta-ses (BCLM) after systemic oncological treatment is between 22 to 27 months [1, 2]. The proper indication for surgical treatment of BCLM is still a matter of discussion [3, 4]. We evaluated the risk factors of surgical treatment of BCLM in 21 women with an average age of 50.9 ±8.9 years. The interval between the breast and the liv...

background :the diagnosis of malignant and potentially malignant epithelial lesions of the oral mucosa cannot be based solely on clinical findings. therefore, histologic evaluation of a representative biopsy specimen is necessary. however the site for the biopsy is always a subjective choice that sometimes raises doubts about its representativeness. colposcopy, a well-known gynecological diagno...

Prof. Carlo Crosti, Clinica Dermatologica, Ospedale San Paolo, Via A Di Rudini, 8, I-20142 Milano (Italy) Despite its frequency, pompholyx or dyshidrotic eczema presents many unresolved problems of aetiology, pathogenesis and therapy. As its invariable histopatholog-ical picture of spongiotic dermatitis indicates, pompholyx is a non-specific reaction somehow related to the particular anatomy of...

The presence of central nervous system (CNS) tissue outside the cranium is often referred to as " heterotopia, " although technically this should be termed " ectopia, " according to the dictionary definition. Glioneuronal heterotopia (GH) is a rare, mass-forming, malformative lesion. Ectopic glioneuronal tissue of the head and neck has been detected in the nasopharynx, oro-pharynx, tongue, pala...

Hormonal disturbances are a possible complication of malignant disease not derived primarily from the endocrine cells. They may result from paraneoplastic hormonal activity of the tumor, such as frequently described Cushing's syndrome in the course of ectopic secretion of adre-nocorticotropic hormone (ACTH), a syndrome of inappropriate secretion of antidiuretic hormone (SIADH) and malignancy re...

Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are a rare and heterogeneous group of tumors arising from the cells of diffuse endocrine system (DES) scattered through the mucosa of the gastrointestinal tract and pancreas. Tumors were historically termed carcinoid-«cancer-like» due to better prognosis than adenocarcinoma. Yearly incidence of GEP-NETs is estimated to be 1-2 of 100.000 po...