Histiocytic necrotising lymphadenitis is the pathognomonic histological appearance of lymph nodes in Kikuchi's disease, a condition characterised by a brief systemic illness and lymphadenopathy. The case is described of a young man, originally diagnosed as having Kikuchi's disease by lymph node histology, who subsequently developed systemic lupus erythematosus with symmetrical polyarthritis, Co...

kikuchi-fujimoto disease (kfd) is a benign, self-limiting disease characterized by histiocytic necrotising lymphadenitis. though several viral agents or an autoimmune etiology has been proposed as causative, the exact cause remains unknown. it has a female predilection and most commonly seen among young asian people. patients usually present with a febrile illness and the presence of lymphadeno...

s: Background: Kikuchi’s disease is a rare, benign, self-limiting disease, mainly involving the lymph nodes of young people. The disease has unknown etiology. Clinical symptoms and basic investigations in a patient often leads to a misdiagnosis, due to similar findings in other lesions like, lymphomas and chronic granulomatous inflammations of lymph nodes like tuberculosis. Lymph node biopsy sh...

Kikuchi-Fujimoto disease (KFD), also known as Kikuchi’s or histiocytic necrotising lymphadenitis, is a rare and benign medical condition of unknown aetiology. It often misdiagnosed lymphoma systemic lupus erythematosus (SLE), leading to inappropriate investigations delayed treatment. thus important for clinicians be cognizant this when assessing patients with cervical lymphadenopathy.

The etiology of cervical lymphadenopathy is multifactorial including infections and tumoral lesions. Histiocytic necrotising lymphadenitis or Kikuchi-Fujimoto's disease is a rare cause of cervical lymphadenopathy which does not have specific clinical signs. We report herewith a case of Kikuchi's disease (KD) diagnosed by histopathology.


 Kikuchi-Fujimoto Disease (KFD) is a rare benign, condition of necrotising histiocytic lymphadenitis. In this case report, we discuss 10 year old male patient who presented with fever, rash and generalised lymphadenopathy that was not attributable to the more common causes. Axillary lymph node biopsy confirmed diagnosis KFD. Treatment prednisolone improved his symptoms but after six month...

To cite: Mannu GS, Ahmed F, Cunnick G, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/ bcr-2013-203100 DESCRIPTION A healthy 19-year-old woman presented to her general practitioner with a 2-month history of a right axillary lump. There were no breast lesions and a general clinical examination was unremarkable. The lump was thought to be an enlarged lymph node ...