this paper reviews the use of texture analysis in studying the performance of hydrophilic matrices of highly soluble drugs and different types of excipients (i.e. water-soluble, water-insoluble and swellable, and water insoluble and non-swellable). tablets were prepared by direct compression, and their swelling and erosion in presence of these different excipients were assessed with the help of...

This paper reviews the use of texture analysis in studying the performance of hydrophilic matrices of highly soluble drugs and different types of excipients (i.e. water-soluble, water-insoluble and swellable, and water insoluble and non-swellable). Tablets were prepared by direct compression, and their swelling and erosion in presence of these different excipients were assessed with the help of...

This paper reviews the use of texture analysis in studying the performance of hydrophilic matrices of highly soluble drugs and different types of excipients (i.e. water-soluble, water-insoluble and swellable, and water insoluble and non-swellable). Tablets were prepared by direct compression, and their swelling and erosion in presence of these different excipients were assessed with the help of...

Due to low cost, ease of administration, and lack need for trained personnel, the oral route is the most convenient and accessible way to design different medicines that could be simply consumed by patients. Regardless of the great benefits of this route, the main challenge in the bioavailability of oral medications is gastrointestinal instability. Nanotechnology is used to improve the solubili...

This paper reviews the use of texture analysis in studying the performance of hydrophilic matrices of highly soluble drugs and different types of excipients (i.e. water-soluble, water-insoluble and swellable, and water insoluble and non-swellable). Tablets were prepared by direct compression, and their swelling and erosion in presence of these different excipients were assessed with the help of...

Potassium chloride (KCl) is a highly water soluble substance which is usually used to prevent hypokalemia. Oil in water disperse phase encapsulation method was used to prepare KCl loaded microcapsules using beeswax and carnauba wax as a hydrophobic matrix. The morphology and characteristics of KCl loaded microspheres were studied using scanning electron microscopy (SEM), photon correlation spec...

potassium chloride (kcl) is a highly water soluble substance which is usually used to prevent hypokalemia. oil in water disperse phase encapsulation method was used to prepare kcl loaded microcapsules using beeswax and carnauba wax as a hydrophobic matrix. the morphology and characteristics of kcl loaded microspheres were studied using scanning electron microscopy (sem), photon correlation spec...

Regardless of the administration route, the key factor for the success and reliability of any formulation is drug bioavailability, defined as the rate and extent at which the active drug is absorbed from a pharmaceutical form and becomes available at the site of drug action.1 Although metabolism and physiological factors highly affect drug absorption by living tissues, bioavailability is strong...