OBJECTIVE Differential meal fat uptake into adipose tissue depots may be a determinant of body fat distribution. RESEARCH DESIGN AND METHODS We used the meal fat tracer/adipose tissue biopsy approach to compare the effects of meal fat content on the fat uptake into visceral and upper and lower body subcutaneous fat depots in 21 premenopausal women. [(3)H]triolein was used to trace the fate of...

The present study was designed to investigate the metabolic and sympathetic responses to a high-fat meal in humans. Fourteen young men (age: 23.6 +/- 0.5 y, BMI: 21.3 +/- 0.4 kg/m2) were examined for energy expenditure and fat oxidation measured by indirect calorimetry for 3.5 h after a high-fat (70%, energy from fat) or an isoenergetic low-fat (20% energy from fat) meal served in random order....

High-fat meal consumption alters the circulating cytokine profile and contributes to cardiometabolic diseases. A prior bout of exercise can ameliorate the triglyceride response to a high-fat meal, but the interactive effects of exercise and high-fat meals on cytokines that mediate cardiometabolic risk are not fully understood. We investigated the effects of prior exercise on the responses of ci...

OBJECTIVES We sought to assess the role of insulin in postprandial blood pressure regulation in the elderly. BACKGROUND Insulin is both a positive inotropic and chronotropic hormone that also vasodilates skeletal muscle vasculature. Insulin may thus mediate aspects of postprandial cardiovascular homeostasis. METHODS Ten healthy elderly subjects were studied in the fasting state on three sep...

1. The responses of blood pressure, heart rate, autonomic function and plasma insulin to a high carbohydrate and a high fat meal of equivalent energy value were studied in nine young volunteers. 2. Neither meal produced a significant change in supine or erect blood pressure. The high carbohydrate meal, however, resulted in an overall rise in both supine (6 beats/min) and erect (6 beats/min; P l...

the aim of the present study was to examine the effect of a bout of long prior aerobic exercise with 70% vo2max on inflammatory marker (svcam-1) and the lipid profile following high fat meal consumption in non–athlete men. plasma concentrations of adhesion molecules and lipid profile are among the most important indicators of the risk of cardiovascular diseases. for this purpose, 20 non–athlete...

The aim of this study was to examine the responses of uric acid, antioxidant defences and pro-oxidant variables after a high-fat meal. Twenty-five healthy persons without criteria for the metabolic syndrome, underwent a high-fat meal with Supracal (60 g fat). Measurements were made at baseline and 3 h after the meal of TAG, uric acid, HDL-cholesterol, total proteins and oxidative stress. Follow...

The consumption of high levels of saturated fat over the course of several weeks may lead to exaggerated cardiovascular reactivity. The consumption of a single high-fat meal has been associated with a transient impairment of vascular function. In a randomized, repeated measures, crossover study we tested whether the consumption of a single high-fat meal by healthy, normotensive participants wou...

To the Editor: Blanco-Colio et al1 showed that a fat-enriched breakfast increased the activation of the transcription factor nuclear factor-kB in peripheral blood mononuclear cells of normal subjects, an effect prevented by antioxidants present in red wine. We compared the effects of a high-fat meal and a high-carbohydrate meal (pizza), with or without dietary antioxidants, on the levels of sol...

Moderate-intensity exercise can lower the TAG response to a high-fat meal; however, the British diet is moderate in fat, and no study to date has compared the effect of such exercise on responses to high-fat and moderate-fat meals. The present work investigated the effect of brisk walking performed 13 h before intake of both high-fat and moderate-fat meals on postprandial plasma TAG concentrati...