objective(s):diabetes plays an important role in the induction of the liver injury. grape seed proanthocyanidin (gsp) have a wide range of medicinal properties against oxidative stress. in this study we evaluated antioxidant effects of gsp on liver in streptozotocin-induced diabetic rats. materials and methods: thirty male sprague–dawley rats were divided into three groups: control, untreated d...

background: the use of devices emitted microwave radiation such as mobile phones, wireless fidelity (wi-fi) routers, etc. is increased rapidly. it has caused a great concern; the researchers should identify its effects on people's health. we evaluated the protective role of vitamin c on the metabolic and enzymatic activities of the liver after exposure to wi-fi routers. material and methods: 70...

objective: arctium lappa (burdock), (a. lappa) root has hypoglycemic and antioxidative effects, and has been used for treatment of diabetes in tradition medicine. this study was conducted to evaluate the antidiabetic and hypolipidemic properties of a. lappa root extract on nicotinamide-streptozotocin (na-stz)-induced type2 diabetes in mice.materials and methods: in this investigation, 70 adult ...

objective(s): particularly in developing countries, selenium and/or iodine deficiencies are encountered and use of pesticides in agriculture are not well-controlled. fenvalerate is a pyrethroid insectide used in agriculture and has applications against a wide range of pests. this study was designed to evaluate the effects of fenvalerate on hepatic and cerebral xenobiotic metabolizing enzyme act...

Hepatic enzyme induction is generally an adaptive response associated with increases in liver weight, induction of gene expression, and morphological changes in hepatocytes. The additive growth and functional demands that initiated the response to hepatic enzyme induction cover a wide range of stimuli including pregnancy and lactation, hormonal fluctuations, dietary constituents, infections ass...

Background: The renin-angiotensin system has an important role in hepatic inflammation and fibrosis. Renin-angiotensin system blockade by angiotensinconverting enzyme (ACE) inhibitors provides some protective effects against hepatic fibrogenesis. Captopril as an ACE inhibitor can decrease inflammatory mediators and attenuate hepatic fibrosis in the livers of bile duct ligated (BDL) rats. Object...

Introduction: Cadmium chloride causes hepatic dysfunction. In the present study, the protective effects of hydroalcoholic extract of Alcea rosea aerial parts were investigated on the hepatic enzyme dysfunction induced by cadmium chloride in adult male rats. Method: In this experimental study, 54 adult male Wistar rats were divided into six groups of 9 as follows; control group, sham group 1 re...

Objective(s):Diabetes plays an important role in the induction of the liver injury. Grape seed proanthocyanidin (GSP) have a wide range of medicinal properties against oxidative stress. In this study we evaluated antioxidant effects of GSP on liver in streptozotocin-induced diabetic rats. Materials and Methods: Thirty male Sprague–Dawley rats were divided into three groups: control, untreated d...