OBJECTIVE To compare the outcomes of preterm infants with respiratory distress initiated on either Heated Humidified High Flow Nasal Cannula or Nasal Continuous Positive Airway Pressure as a primary mode of respiratory support. STUDY DESIGN Prospective observational cohort study. SETTING Tertiary care level III neonatal intensive care unit. PARTICIPANTS 88 preterm infants between 28 to 34...

OBJECTIVE High-flow humidified nasal cannula is often used to provide noninvasive respiratory support in children. The effect of high-flow humidified nasal cannula on effort of breathing in children has not been objectively studied, and the mechanism by which respiratory support is provided remains unclear. This study uses an objective measure of effort of breathing (Pressure. Rate Product) to ...

The use of heated humidified high-flow nasal cannula (HFNC) as an alternative to CPAP in neonates has increased in recent years and seems to have gone viral.1 HFNC as a method of respiratory support to aid in extubation has increased in popularity following randomized controlled trials showing no difference in extubation failure rates or other outcomes between HFNC and CPAP in neonates at 26 we...

Heated humidified high-flow nasal cannula therapy (HHHFNC) was originally described as a mode of respiratory support in premature neonates and is now increasingly used in the management of acute respiratory failure in older infants and children. Heating and humidification of gas mixtures allow comfortable delivery of flow rates that match or exceed the patient's inspiratory flow rate. Emerging ...

The treatment of choice for patients with respiratory failure of neuromuscular origin, especially in patients with hypercapnic respiratory acidosis, is noninvasive ventilation (NIV). Endotracheal intubation and invasive ventilation are indicated for patients with severe respiratory compromise or failure of NIV. In recent years, high-flow oxygen therapy and active humidification devices have bee...

Introduction Oxygen therapy is generally provided via nasal cannula, non-rebreathing masks and masks with reservoir bags. These devices have various limitations. Despite showing clear benefits in certain conditions, non-invasive positive pressure ventilation (NIPPV) limits mobilization, restricts communication and oral nutrition and is poorly tolerated by some patients due to discomfort. High-f...

The most conventional forms of oxygen delivery rely on facemasks, a nasal cannula or nasal prongs. However, the use of these methods is limited by certain drawbacks, including the need for a flow of oxygen higher than 15L/min in case of severe hypoxemia or the dilution of administered oxygen by entrained room air in cases of high inspiratory flow. An alternative to conventional oxygen therapy h...