objecttive(s): despite the poor mechanical properties of hydroxyapatite, its unique biological properties leads we think about study on improving its properties rather than completely replacing it with other biomaterials. accordingly, in this study we introduced hydroxyapatite reinforced with hardystonite as a novel bio-nanocompositeand evaluate its in-vitro bioactivity with the aim of developi...

Objecttive(s): Despite the poor mechanical properties of hydroxyapatite, its unique biological properties leads we think about study on improving its properties rather than completely replacing it with other biomaterials. Accordingly, in this study we introduced hydroxyapatite reinforced with hardystonite as a novel bio-nanocompositeand evaluate its in-vitro bioactivity with the aim of developi...

objective(s): hardystonite (ht) has been successfully prepared by a modified sol-gel method. we hypothesized thatnano-sized (ht) would mimic more efficiently the nanocrystal structure and function of natural bone apatite, owing to the higher surface area, compare to conventional micron-size (ht).materials and methods: the hardystonite nanopowder was prepared via a modified sol-gel method.optimi...

In this study, mechanical properties and apatite formation ability of synthesized fluorapatite-hardystonite (FA-HT) nanocomposite scaffolds were investigated. Hardystonite (HT; 5 and 10 wt.%) as a reinforcement phase was incorporated into the FA scaffold. FA was mixed with HT for 4 h under argon gas at 220 °C. A space holder method was used for fabricating porous FA-HT scaffolds. Sodium chlorid...

objective(s): hardystonite (ht) is zn-modified silicate bioceramics with promising results for bone tissue regeneration. however, ht possesses no obvious apatite formation. thus, in this study we incorporated sr and ti into ht to prepare sr-ti-hardystonite (sr-ti-ht) nanocomposite and evaluated its in vitro bioactivity with the purpose of developing a more bioactive bone substitute material. ma...

Objective(s): Hardystonite (HT) is Zn-modified silicate bioceramics with promising results for bone tissue regeneration. However, HT possesses no obvious apatite formation. Thus, in this study we incorporated Sr and Ti into HT to prepare Sr-Ti-hardystonite (Sr-Ti-HT) nanocomposite and evaluated its in vitro bioactivity with the purpose of developing a more bioactive bone substitute material. Ma...

Objective(s): Hardystonite (HT) has been successfully prepared by a modified sol-gel method. We hypothesized thatnano-sized (HT) would mimic more efficiently the nanocrystal structure and function of natural bone apatite, owing to the higher surface area, compare to conventional micron-size (HT).Materials and Methods: The hardystonite nanopowder was prepared via a modified sol-gel method.Optimi...

Tissue engineering strategies to construct vascularized bone grafts are now attracting much attention. Strontium-hardystonite-Gahnite (Sr-HT-Gahnite) is a strong, highly porous, and biocompatible calcium silicate based bio-ceramic that contains strontium and zinc ions. Adipose derived stem cells (ASCs) have been demonstrated to have the ability in promoting osteogenesis and angiogenesis. In thi...

Altering the CaO to ZnO ratio of alkali borosilicate glass, in favour ZnO, causes phase separation with hardystonite-like (Ca 2 ZnSi O 7 ) and willemite-like (ZnSi 4 structures identified. This is concurrent increased glass durability.